{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T12:17:28Z","timestamp":1793881048564,"version":"4.7.0"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Addis Ababa university college of Medicine and Health Science"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Parasitology Research"],"published-print":{"date-parts":[[2021,4,12]]},"abstract":"<jats:p>Introduction. Malaria is a protozoan disease transmitted by the bite of infected female Anopheles mosquitoes. Progression to severe and fatal disease is largely but not entirely confined to Plasmodium falciparum infections. Malaria is a major public health problem in Ethiopia despite relatively low malaria prevalence compared to most other malaria-endemic countries in Africa. In Ethiopia, a nationwide report during 2015 showed that the total number of deaths associated with malaria was 1561. Methods. A retrospective cross-sectional study was conducted in Arba Minch General Hospital on February 2019. Data were collected from a patient record who was admitted with severe malaria in the past four years from Sept. 2015 to Aug. 2018. Results. This study included a total of 387 patients with severe malaria. The mortality rate associated with severe malaria in the year between 2015 and 2018 at Arba Minch General Hospital was 5.7%. Comorbidity, impaired consciousness, and acidosis were significantly associated with mortality, at significant level of <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>. Conclusions. Comorbidity, impaired consciousness, and acidosis were found to be poor prognostic indicators for patients with severe malaria.<\/jats:p>","DOI":"10.1155\/2021\/6664070","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T15:50:18Z","timestamp":1618242618000},"page":"1-6","source":"Crossref","is-referenced-by-count":8,"title":["Treatment Outcome of Severe Malaria and Associated Factors among Adults Admitted in Arba Minch General Hospital, Southern Nation Nationality and People\u2019s Region, Ethiopia"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0298-7895","authenticated-orcid":true,"given":"Solomon K.","family":"Bekele","sequence":"first","affiliation":[{"name":"Arba Minch University College of Medicine and Health Science, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muluken B.","family":"Ayele","sequence":"additional","affiliation":[{"name":"Arba Minch University College of Medicine and Health Science, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmare G.","family":"Mihiret","sequence":"additional","affiliation":[{"name":"Arba Minch University College of Medicine and Health Science, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6338-4222","authenticated-orcid":true,"given":"Negalign G.","family":"Dinegde","sequence":"additional","affiliation":[{"name":"Addis Ababa University College of Health Sciences, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussen","family":"Mekonen","sequence":"additional","affiliation":[{"name":"Addis Ababa University College of Health Sciences, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gesila E.","family":"Yesera","sequence":"additional","affiliation":[{"name":"Arba Minch University College of Medicine and Health Science, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","volume-title":"Brunner and Suddarth\u2019s Textbook of Medical-Surgical Nursing","author":"J. 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