{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T03:11:33Z","timestamp":1776395493693,"version":"3.51.2"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T00:00:00Z","timestamp":1615593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Applied Bionics and Biomechanics"],"published-print":{"date-parts":[[2021,3,13]]},"abstract":"<jats:p>A pathological disorder of human penile function, known as Peyronie\u2019s disease, is characterized by the formation of plaque particles within the tunica albuginea. The plagues in the shape of rigid plate form in the scars as a result of the imperfect healing process. Due to high stiffness, plagues are the source of pain and anomalous deformations during erectile penis function. The authors simulate the biomechanical behavior of the penile structure by a 3D finite element model. The numerical model is based on the real geometrical shape and the tissue structure with consideration of large nonlinear deformations. The penile erection is modeled by the initial strains imposed on the corpus cavernosa. The stress analysis is performed in a case study of various plague locations. The Peyronie\u2019s syndrome manifested by the penis angular deviation simulated by the analysis is compared with the clinical data. The computational simulations provide a rational explanation for the clinical observations on patients. The objective is to apply the proposed modeling approach for the development and validation of treatment methods based on the application of shock waves.<\/jats:p>","DOI":"10.1155\/2021\/6669822","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T18:20:09Z","timestamp":1615832409000},"page":"1-6","source":"Crossref","is-referenced-by-count":12,"title":["Biomechanical Simulation of Peyronie\u2019s Disease"],"prefix":"10.1155","volume":"2021","author":[{"given":"Pavel","family":"Drl\u00edk","sequence":"first","affiliation":[{"name":"Central Military Hospital in Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1150-8171","authenticated-orcid":true,"given":"Vladim\u00edr","family":"\u010cervenka","sequence":"additional","affiliation":[{"name":"Cervenka Consulting s.r.o., Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4945-1163","authenticated-orcid":true,"given":"Jan","family":"\u010cervenka","sequence":"additional","affiliation":[{"name":"Cervenka Consulting s.r.o., Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"425","article-title":"Sur quelques obstacles qui s\u2019opposent \u00e1 l\u2019ejaculation naturele de la semence","volume":"1","author":"F. 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Drlik","year":"2020"}],"container-title":["Applied Bionics and Biomechanics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/abb\/2021\/6669822.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/abb\/2021\/6669822.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/abb\/2021\/6669822.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T18:20:14Z","timestamp":1615832414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/abb\/2021\/6669822\/"}},"subtitle":[],"editor":[{"given":"Qiguo","family":"Rong","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,3,13]]},"references-count":8,"alternative-id":["6669822","6669822"],"URL":"https:\/\/doi.org\/10.1155\/2021\/6669822","relation":{},"ISSN":["1754-2103","1176-2322"],"issn-type":[{"value":"1754-2103","type":"electronic"},{"value":"1176-2322","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3,13]]}}}