{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:33:51Z","timestamp":1787236431818,"version":"build-2736575974"},"reference-count":56,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T00:00:00Z","timestamp":1629676800000},"content-version":"vor","delay-in-days":234,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Asthma is an important reason for hospitalization in children aged under five years. Information about the current status of asthma in Iranian children can help the Iranian health sector plan carefully and prevent asthma incidence by educating the families. The present systematic review and meta\u2010analysis is aimed at estimating asthma prevalence in Iranian children and adolescents.\n                    <jats:italic>Method<\/jats:italic>\n                    . Data were found using keywords such as prevalence, epidemiology, asthma, adolescent, children, pediatrics, Iran in Web of Science, Scopus, PubMed, Cochrane, and Embase databases. Three national databases, including Magiran, Barakat Pharmed Co (Iran medex), and Scientific Information Databank (SID) were searched until 1 October 2020. Cross\u2010sectional and original studies were included in the study, and then, quality assessment was done using the National Institutes of Health\u2019s Quality Assessment Tool for Observational Cohort and Cross\u2010Sectional Studies. A pooled estimated prevalence of asthma was calculated using Der Simonian\u2010Laird random model. Egger\u2019s test was used to evaluate publication bias. The data were analyzed using the STATA software version 16.\n                    <jats:italic>Results<\/jats:italic>\n                    . 30 studies were selected and investigated. The prevalence of asthma in children and adolescents was 6% and 8%, and the prevalence in boys and girls was 9% and 8%, respectively. Among the asthma symptoms, wheezing had the most prevalence (17% in children and 19% in adolescents) and sleep disturbance had the lowest prevalence (6% in children and 6% in adolescents).\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . The prevalence of asthma in Iranian children and adolescents is lower than in the world. Existing strategies should be pursued followed. Also, guidelines for asthma control and prevention should be considered in the future.\n                  <\/jats:p>","DOI":"10.1155\/2021\/6671870","type":"journal-article","created":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T16:20:14Z","timestamp":1629735614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["The Prevalence of Asthma among Iranian Children and Adolescent: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1155","volume":"2021","author":[{"given":"Neda","family":"Rahimian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Aghajanpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Jouybari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Ataee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asadollah","family":"Fathollahpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasrin","family":"Lamuch-Deli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesam","family":"Kooti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6351-2909","authenticated-orcid":false,"given":"Rasoul Nasiri","family":"Kalmarzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,23]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h996"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2018.00186"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aller.2018.10.001"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/02770903.2017.1362423"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.2165\/11597420-000000000-00000"},{"key":"e_1_2_10_6_2","first-page":"217","article-title":"Prevalence of asthma symptom in Iran: a meta-analysis","volume":"31","author":"Heidarnia M. 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