{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:04:39Z","timestamp":1793289879932,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Interventional Cardiology"],"published-print":{"date-parts":[[2021,3,24]]},"abstract":"<jats:p>Introduction. The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. Instead, the management of a concomitant CAD remains unclear. We evaluate the impact of CAD and percutaneous coronary intervention (PCI) on TAVI procedures. Materials and Methods. A retrospective study was conducted on 1336 consecutive patients who underwent TAVI in Toulouse University Hospital, Rangueil, France. The studied population was divided into 2 groups: CAD-TAVI group and No CAD-TAVI group. Then, the CAD-TAVI group was segregated into 2 subgroups: PCI-TAVI group and No PCI-TAVI group. In-hospital adverse clinical outcomes were assessed in each group. Results. Pre-TAVI work-up revealed significant CAD in 36% of 1030 patients eligible for inclusion in the study. The overall prevalence of in-hospital death, stroke, major or life-threatening bleeding, minor bleeding, major vascular complications, minor vascular complications, pacemaker implantation, and acute kidney injury was 2.7%, 2.4%, 2.8%, 3.6%, 3.9%, 7.5%, 12.5%, and 2.7%, respectively. Among the studied population, 55% were admitted to the cardiac care unit. No significant statistical difference was observed between groups. Discussion. CAD-TAVI population was not more likely to develop in-hospital adverse clinical outcomes post-TAVI procedure compared to others. Also, no significant difference regarding in-hospital death was observed. In parallel, performing PCI prior to TAVI did not increase the risk of in-hospital death and complications. The difference in terms of the distribution of antithrombotic regimen may explain the higher prevalence of bleeding events in the PCI-TAVI group. Conclusion. This study provides direct clinical relevance useful in daily practice. No negative impact has been attributed to the presence of a concomitant CAD and\/or preoperative PCI on the TAVI hospitalization period.<\/jats:p>","DOI":"10.1155\/2021\/6672400","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T15:22:57Z","timestamp":1616685777000},"page":"1-7","source":"Crossref","is-referenced-by-count":14,"title":["Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3338-0842","authenticated-orcid":true,"given":"Anthony G.","family":"Matta","sequence":"first","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"},{"name":"Faculty of Medicine, Holy Spirit University of Kaslik, Jounieh, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibault","family":"Lhermusier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Campelo","family":"Parada","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Bouisset","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronan","family":"Canitrot","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Nader","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Blanco","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meyer","family":"Elbaz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Roncalli","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Carri\u00e9","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.09.028"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.117.005593"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1814052"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1816885"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.10.057"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.12.033"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22501"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.4244\/eijv7i5a90"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.03.089"},{"issue":"2","key":"10","first-page":"69","article-title":"Coronary revascularization in transcatheter aortic valve implantation candidates: why, who, when?","volume":"12","author":"D. 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