{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T02:48:48Z","timestamp":1777085328294,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2021,4,19]]},"abstract":"<jats:p>We report a case of a newborn with two synchronous tumors\u2014sialoblastoma and hepatoblastoma\u2014diagnosed at 20 weeks of gestation by magnetic resonance imaging (MRI) and ultrasonography (US). The aim of this study was to describe the management of this case together with a review of the literature. Our patient had a large facial tumor associated with extremely high alpha-fetoprotein levels. Diagnosis of the tumors was made by surgical biopsy, showing typical features in both. Sialoblastoma is a potentially aggressive tumor. In our case, the Ki67 index in the sialoblastoma was between 20 and 30%, indicating a possibly unfavorable behavior. The infant underwent surgery and chemotherapy in different steps. Complete surgical resection with clean margins is considered to be the best treatment option for sialoblastoma. Only four similar cases were previously reported. Timely management by a multidisciplinary team is essential in these difficult cases. In our patient, outcome was good at the time of this report.<\/jats:p>","DOI":"10.1155\/2021\/6674372","type":"journal-article","created":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T23:06:50Z","timestamp":1618873610000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Two Synchronous Neonatal Tumors: An Extremely Rare Case"],"prefix":"10.1155","volume":"2021","author":[{"given":"M.","family":"Rodr\u00edguez-Zubieta","sequence":"first","affiliation":[{"name":"Department of Pathology, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Albarenque","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lagues","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"San Roman","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Varela","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Russo","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Podesta","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery and Transplantation, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Schauvinhold","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Etchegaray","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Hospital Universitario Austral, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3561-5035","authenticated-orcid":true,"given":"M. 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