{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T23:01:54Z","timestamp":1744758114488,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:00:00Z","timestamp":1612915200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005117","name":"Birjand University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005117","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Immunology Research"],"published-print":{"date-parts":[[2021,2,10]]},"abstract":"<jats:p>Background. The inflammatory mucosa of the sinus cavities is called sinusitis and is divided into various types based on its appearance and sign. Chronic rhinosinusitis is an inflammatory-infectious disease that involves the frontal, sphenoid, ethmoid, and maxillary sinuses. Chronic sinusitis is a multifactorial disease and the range of causes varies from environmental factors to genetic factors. The purpose of this study was to compare blood and tissue eosinophils and serum IgE levels in patients with chronic sinusitis with nasal polyp in Vali-e-Asr hospital in 1397. Methods. In this descriptive-analytical study, the population under study included those with chronic sinusitis referred to Birjand Valiasr Hospital in 1397.3\u2009cc of blood samples were taken 1 day before surgery to evaluate eosinophil counts and serum IgE levels. Also, samples taken from patients during surgery were counted, and then, 100 cells were counted, and eosinophil counts and percentages were calculated. The data were entered into the SPSS software after data collection. Results. This study was performed on 70 patients with chronic rhinosinusitis which included 43 men (61.4%) and 27 women (38.6%) with mean age of <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>39.11<\/a:mn>\n                        <a:mo>\u00b1<\/a:mo>\n                        <a:mn>13<\/a:mn>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mn>13.72<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula> years. There was no significant difference between sex of patients and mean serum IgE level (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). The mean percentage of eosinophils in blood samples and tissues of patients with chronic sinusitis was significantly increased with the increase in CT scan (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Conclusions. Tissue or blood eosinophilia was not observed in patients with chronic rhinosinusitis. Also, the mean eosinophil percentage of blood and tissue increased significantly in patients with increased scanning computed tomography (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>).<\/jats:p>","DOI":"10.1155\/2021\/6680676","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T19:50:46Z","timestamp":1612986646000},"page":"1-5","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of Blood and Tissue Eosinophil Count and Blood IgE in Patients with Chronic Sinusitis and Nasal Polyps"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7709-2861","authenticated-orcid":true,"given":"Masoud","family":"Asghari","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, School of Medicine, Birjand University of Medical Sciences, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9260-8723","authenticated-orcid":true,"given":"Shadi","family":"Izadpanahi","sequence":"additional","affiliation":[{"name":"Birjand University of Medical Sciences, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7569-6776","authenticated-orcid":true,"given":"Mina Heidari","family":"Esfahani","sequence":"additional","affiliation":[{"name":"Shiraz University of Medical Science (SUMS), Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"42","key":"1","first-page":"577","article-title":"Lymphocyte subsets (CD3, CD4, CD8), CD4\/CD8 ratio of sinus mucosa and measured serum IgE level in adults with","volume":"11","author":"T. Fathi Najafi","year":"2004","journal-title":"Razi Journal of Medical Sciences"},{"volume-title":"Head & Neck Surgery--Otolaryngology","year":"2006","author":"B. J. Bailey","key":"2"},{"issue":"92","key":"3","first-page":"87","article-title":"The correlation of nasal mucosal and systemic eosinophilia with chronic rhinosinusitis","volume":"22","author":"S. A. Madani","year":"2012","journal-title":"Journal of Mazandaran University of Medical Sciences"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200307000-00016"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70007-X"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.06.726"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-200301000-00007"},{"issue":"3","key":"8","article-title":"Microbiology and antimicrobial resistance in chronic resistant rhino sinusitis with or without polyp after functional endoscopic sinus surgery","volume":"10","author":"S. HASHEMI","year":"2005","journal-title":"Journal of Research in Medical Sciences"},{"volume-title":"Diseases of Ear, Nose & Throat","year":"2010","author":"P. Dhingra","key":"9"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1177\/194589240301700106"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.07.049"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3948"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70152-4"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.suppl_2.S79"},{"issue":"10","key":"15","first-page":"363","article-title":"Nasal eosinophils correlate with FEV1 in patients with perennial allergic rhinitis associated to asthma","volume":"36","author":"G. Ciprandi","year":"2004","journal-title":"European annals of allergy and clinical immunology"},{"issue":"1","key":"16","first-page":"23","article-title":"Eosinophil count in nasal secretions of subjects with and without nasal symptoms","volume":"38","author":"R. Jankowski","year":"2000","journal-title":"Rhinology"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1159\/000086075"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v2.i12.873"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1038\/srep27615"},{"issue":"50","key":"20","first-page":"99","article-title":"Fungal infection in patients with nasal polyposis in two groups with high and normal serum IgE referred to Rasoul-e-Akram Hospital for ENT surgery","volume":"13","author":"A. Tabatabaee","year":"2006","journal-title":"Razi Journal of Medical Sciences"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2017\/25320.9445"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1186\/s40248-017-0102-7"}],"container-title":["Journal of Immunology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jir\/2021\/6680676.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jir\/2021\/6680676.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jir\/2021\/6680676.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T19:50:54Z","timestamp":1612986654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jir\/2021\/6680676\/"}},"subtitle":[],"editor":[{"given":"Luis Alberto","family":"Ponce-Soto","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,2,10]]},"references-count":22,"alternative-id":["6680676","6680676"],"URL":"https:\/\/doi.org\/10.1155\/2021\/6680676","relation":{},"ISSN":["2314-7156","2314-8861"],"issn-type":[{"type":"electronic","value":"2314-7156"},{"type":"print","value":"2314-8861"}],"subject":[],"published":{"date-parts":[[2021,2,10]]}}}