{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T03:33:29Z","timestamp":1782704009130,"version":"3.54.5"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005756","name":"Shahrekord University of Medical Sciences","doi-asserted-by":"publisher","award":["IR.SKUMS.REC.1394.145"],"award-info":[{"award-number":["IR.SKUMS.REC.1394.145"]}],"id":[{"id":"10.13039\/501100005756","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005756","name":"Shahrekord University of Medical Sciences","doi-asserted-by":"publisher","award":["ZUMS-543"],"award-info":[{"award-number":["ZUMS-543"]}],"id":[{"id":"10.13039\/501100005756","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005756","name":"Shahrekord University of Medical Sciences","doi-asserted-by":"publisher","award":["950612"],"award-info":[{"award-number":["950612"]}],"id":[{"id":"10.13039\/501100005756","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008323","name":"Zanjan University of Medical Sciences","doi-asserted-by":"publisher","award":["IR.SKUMS.REC.1394.145"],"award-info":[{"award-number":["IR.SKUMS.REC.1394.145"]}],"id":[{"id":"10.13039\/501100008323","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008323","name":"Zanjan University of Medical Sciences","doi-asserted-by":"publisher","award":["ZUMS-543"],"award-info":[{"award-number":["ZUMS-543"]}],"id":[{"id":"10.13039\/501100008323","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008323","name":"Zanjan University of Medical Sciences","doi-asserted-by":"publisher","award":["950612"],"award-info":[{"award-number":["950612"]}],"id":[{"id":"10.13039\/501100008323","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Biotechnology Development Council","award":["IR.SKUMS.REC.1394.145"],"award-info":[{"award-number":["IR.SKUMS.REC.1394.145"]}]},{"name":"Biotechnology Development Council","award":["ZUMS-543"],"award-info":[{"award-number":["ZUMS-543"]}]},{"name":"Biotechnology Development Council","award":["950612"],"award-info":[{"award-number":["950612"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2021,2,9]]},"abstract":"<jats:p>Thymus (Lamiaceae) is famous for its pharmacological properties. Thymus daenensis Celak (Avishan-e-denaee in Persian) is an endemic Thymus species in Iran and is traditionally used for its digestive, carminative, antitussive, antispasmodic, and expectorant attributes in folk medicine. Ecotypic oils were extracted and analyzed with the GC-MS. Their biological properties in terms of antimicrobial, antioxidant, and antigenotoxic activities were evaluated using the minimal inhibitory concentration, minimal bactericidal concentration, and DPPH, \u03b2-carotene, and comet assays. The GC-MS results for Thymus daenensis Celak oils revealed thymol (73.86%) and carvacrol (51.89%) as the most abundant components. Due to the results, reasonable bactericidal activity values range from 0.14 to 5.00\u2009mg\/ml, and fungicidal activity ranges from 0.17 to 0.58\u2009mg\/ml. The necessary oil free radical scavenging capacity (0.41\u20131.79\u2009mg\/ml), bleaching inhibitory activity (0.01\u20131.06\u2009mg\/ml), and genoprotective potential (1.04\u20137.78\u2009mg\/ml) indicated the dose-dependent activity. The results suggest that Thymus daenensis is an important antibacterial and antifungal bioresource. Additionally, the antioxidant and radical scavenging capacity suggests this species has a role as a natural preservative in oxidative diseases and in the prevention of food spoilage.<\/jats:p>","DOI":"10.1155\/2021\/6686558","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T20:06:23Z","timestamp":1612987583000},"page":"1-12","source":"Crossref","is-referenced-by-count":5,"title":["Ecotypic Variations Affected the Biological Effectiveness of Thymus daenensis Celak Essential Oil"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1489-4047","authenticated-orcid":true,"given":"Fatemeh","family":"Elahian","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1139-1700","authenticated-orcid":true,"given":"Maryam","family":"Garshasbi","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy and Traditional Pharmaceuticals, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2794-156X","authenticated-orcid":true,"given":"Zahra","family":"Mehri Asiabar","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy and Traditional Pharmaceuticals, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1033-5237","authenticated-orcid":true,"given":"Neda","family":"Gholamian Dehkordi","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6776-1395","authenticated-orcid":true,"given":"Alireza","family":"Yazdinezhad","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy and Traditional Pharmaceuticals, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0307-3750","authenticated-orcid":true,"given":"Seyed Abbas","family":"Mirzaei","sequence":"additional","affiliation":[{"name":"Clinical Biochemistry Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9268468"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2014.10.042"},{"issue":"10","key":"3","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.3390\/molecules14104213","article-title":"Chemical composition and in vitro antimicrobial and mutagenic activities of seven Lamiaceae essential oils","volume":"14","author":"L. 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Ghaderi","year":"2017","journal-title":"Journal of Applied Microbiology"},{"issue":"4","key":"6","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1111\/nph.12865","article-title":"How light competition between plants affects their response to climate change","volume":"203","author":"M. P. van Loon","year":"2014","journal-title":"New Phytologist"},{"issue":"6","key":"7","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1002\/ffj.3333","article-title":"Diversity and ecotypic variation in the antioxidant and antigenotoxic effects of Thymus kotschyanus Boiss & Hohen","volume":"31","author":"V. 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