{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T07:56:10Z","timestamp":1773388570077,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T00:00:00Z","timestamp":1613174400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Tianjin Haihe Hospital Science and Technology Fund","award":["HHYY-202001"],"award-info":[{"award-number":["HHYY-202001"]}]},{"name":"Tianjin Haihe Hospital Science and Technology Fund","award":["2020xkz02"],"award-info":[{"award-number":["2020xkz02"]}]},{"name":"Tianjin Haihe Hospital Science and Technology Fund","award":["2020xkm03"],"award-info":[{"award-number":["2020xkm03"]}]},{"name":"Tianjin Health Science and Technology Project","award":["HHYY-202001"],"award-info":[{"award-number":["HHYY-202001"]}]},{"name":"Tianjin Health Science and Technology Project","award":["2020xkz02"],"award-info":[{"award-number":["2020xkz02"]}]},{"name":"Tianjin Health Science and Technology Project","award":["2020xkm03"],"award-info":[{"award-number":["2020xkm03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2021,2,13]]},"abstract":"<jats:p>We aimed to investigate changes in pulmonary function and computed tomography (CT) findings in patients with coronavirus disease 2019 (COVID-19) during the recovery period. COVID-19 patients underwent symptom assessment, pulmonary function tests, and high-resolution chest CT 6 months after discharge from the hospital. Of the 54 patients enrolled, 31 and 23 were in the moderate and severe group, respectively. The main symptoms 6 months after discharge were fatigue and exertional dyspnea, experienced by 24.1% and 18.5% of patients, respectively, followed by smell and taste dysfunction (9.3%) and cough (5.6%). One patient dropped out of the pulmonary function tests. Of the remaining 54 patients, 41.5% had pulmonary dysfunction. Specifically, 7.5% presented with restrictive ventilatory dysfunction (forced vital capacity &lt;80% of the predicted value), 18.9% presented with small airway dysfunction, and 32.1% presented with pulmonary diffusion impairment (diffusing capacity for carbon monoxide &lt;80% of the predicted value). Of the 54 patients enrolled, six patients dropped out of the chest CT tests. Eleven of the remaining 48 patients presented with abnormal lung CT findings 6 months after discharge. Patients with residual lung lesions were more common in the severe group (52.6%) than in the moderate group (3.4%); a higher proportion of patients had involvement of both lungs (42.1% vs. 3.4%) in the severe group. The residual lung lesions were mainly ground-glass opacities (20.8%) and linear opacities (14.6%). Semiquantitative visual scoring of the CT findings revealed significantly higher scores in the left, right, and both lungs in the severe group than in the moderate group. COVID-19 patients 6 months after discharge mostly presented with fatigue and exertional dyspnea, and their pulmonary dysfunction was mostly characterized by pulmonary diffusion impairment. As revealed by chest CT, the severe group had a higher prevalence of residual lesions than the moderate group, and the residual lesions mostly manifested as ground-glass opacities and linear opacities.<\/jats:p>","DOI":"10.1155\/2021\/6692409","type":"journal-article","created":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T04:56:32Z","timestamp":1613278592000},"page":"1-7","source":"Crossref","is-referenced-by-count":36,"title":["A Follow-Up Study of Lung Function and Chest Computed Tomography at 6 Months after Discharge in Patients with Coronavirus Disease 2019"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4693-3159","authenticated-orcid":true,"given":"Qian","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin 300350, China"},{"name":"Tianjin Institute of Respiratory Diseases, Tianjin 300350, 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