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Respiratory viruses such as influenza, respiratory syncytial virus, SARS-CoV-2, and adenovirus, are among the most common causes of respiratory illness in humans, spreading as pandemics or epidemics throughout all continents. Nanotechnologies are particles in the nanometer range made from various compositions. They can be lipid-based, polymer-based, protein-based, or inorganic in nature, but they are all bioinspired and virus-like. In this review, we aimed to present a short review of the different nanoparticles currently studied, in particular those which led to publications in the field of respiratory viruses. We evaluated those which could be beneficial for respiratory disease-based viruses; those which already have contributed, such as lipid nanoparticles in the context of COVID-19; and those which will contribute in the future either as vaccines or antiviral drug delivery systems. We present a short assessment based on a critical selection of evidence indicating nanotechnology\u2019s promise in the prevention and treatment of respiratory infections.<\/jats:p>","DOI":"10.1155\/2021\/6741290","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T23:50:22Z","timestamp":1635378622000},"page":"1-28","source":"Crossref","is-referenced-by-count":11,"title":["Contribution of Nanotechnologies to Vaccine Development and Drug Delivery against Respiratory Viruses"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-170X","authenticated-orcid":true,"given":"Mahdi","family":"Ftouh","sequence":"first","affiliation":[{"name":"Drug Development Laboratory LR12ES09, Faculty of Pharmacy, University of Monastir, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0619-3395","authenticated-orcid":true,"given":"Nesrine","family":"Kalboussi","sequence":"additional","affiliation":[{"name":"Drug Development Laboratory LR12ES09, Faculty of Pharmacy, University of Monastir, Tunisia"},{"name":"Sahloul University Hospital, Pharmacy Department, Sousse, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5318-3654","authenticated-orcid":true,"given":"Nabil","family":"Abid","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, High Institute of Biotechnology of Sidi Thabet, University of Manouba, BP-66, 2020 Ariana, Tunis, Tunisia"},{"name":"Laboratory of Transmissible Diseases and Biological Active Substances LR99ES27, Faculty of Pharmacy, University of Monastir, Rue Ibn Sina, 5000 Monastir, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6822-2855","authenticated-orcid":true,"given":"Souad","family":"Sfar","sequence":"additional","affiliation":[{"name":"Drug Development Laboratory LR12ES09, Faculty of Pharmacy, University of Monastir, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3323-2997","authenticated-orcid":true,"given":"Nathalie","family":"Mignet","sequence":"additional","affiliation":[{"name":"University of Paris, INSERM, CNRS, UTCBS, Facult\u00e9 de Pharmacie, 4 avenue de l\u2019Observatoire, 75006 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7512-1331","authenticated-orcid":true,"given":"Badr","family":"Bahloul","sequence":"additional","affiliation":[{"name":"Drug Development Laboratory LR12ES09, Faculty of Pharmacy, University of Monastir, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","article-title":"histoire - Grippe et autres maladies virales, rappels historiques des grandes pand\u00e9mies","author":"E. 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