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BNT162b2 is an mRNA\u2010based vaccine, which is promising and safe for use during pregnancy, as it could help prevent SARS\u2010CoV\u20102 infection and its complications during pregnancy. Other vaccines, such as influenza and Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis) vaccines, provide significant protection for babies. Recent studies have shown that COVID\u201019 antibodies are present in newborns at birth, owing to maternal BNT162b2 vaccination during pregnancy; however, it is currently unclear how long these antibodies could protect infants from SARS\u2010CoV\u20102 infection and its complications. Herein, we present the case of a preterm baby born at 33 weeks via an emergency cesarean section owing to maternal complications. The mother had received two doses of the BNT162b2 vaccine at 22 and 26 weeks of gestation. Positive anti\u2010SARS\u2010CoV\u20102 S antibodies were detected in the infant at 2 weeks, 6 weeks, 3 months, and 6 months of age. This is the first case report in which BNT162b2 vaccination during pregnancy yielded a persistent immune response in an infant at 6 months of age. The declining anti\u2010SARS\u2010CoV\u20102 S antibody titers noted at 6 months of age emphasize the need for the vaccination of children at this age.<\/jats:p>","DOI":"10.1155\/2021\/6901131","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T13:21:23Z","timestamp":1634131283000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["BNT162b2 Vaccination during Pregnancy Protects Both the Mother and Infant: Anti\u2010SARS\u2010CoV\u20102 S Antibodies Persistently Positive in an Infant at 6 Months of Age"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5671-9485","authenticated-orcid":false,"given":"Chetna","family":"Mangat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasa","family":"Milosavljevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001316"},{"volume-title":"2019-nCoV Outbreak Is an Emergency of International Concern","key":"e_1_2_8_3_2"},{"volume-title":"Coronavirus Disease (COVID-19) Pandemic","key":"e_1_2_8_4_2"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6924e2"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6939e1"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01397-4"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiab410"},{"key":"e_1_2_8_9_2","unstructured":"FDA takes key action in fight against COVID-19 by issuing emergency use authorization for first COVID-19 vaccine 2021 https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-takes-key-action-fight-against-covid-19-issuing-emergency-use-authorization-first-covid-19."},{"key":"e_1_2_8_10_2","unstructured":"FDA takes additional action in fight against COVID-19 by issuing emergency use authorization for second COVID-19 vaccine 2021 https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-takes-additional-action-fight-against-covid-19-issuing-emergency-use-authorization-second-covid."},{"key":"e_1_2_8_11_2","unstructured":"FDA issues emergency use authorization for third COVID-19 vaccine 2021 https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-issues-emergency-use-authorization-third-covid-19-vaccine."},{"key":"e_1_2_8_12_2","unstructured":"FDA approves first COVID-19 vaccine. 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