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This affects the nutritional status of patients and requires multidimensional interventions including nutritional interventions according to individual metabolic needs. Our scoping review determined the effects of antioxidants in the treatment of COPD patients and their role in the decrease in the probability of exacerbations, hospital readmissions, and changes in lung function. The sources MEDLINE, LILACS, and Google Scholar were consulted and 19 studies were selected. The most indicated antioxidants are N-Acetylcysteine, vitamins E and D, and Zinc. Other antioxidants from plants or fruits extracts are also being investigated. The beneficial effect of antioxidants in stable or exacerbated patients is not clear, but theoretical and biological arguments of benefit justify lines of research that specify the impact on reducing oxidative stress and negative effects in COPD.<\/jats:p>","DOI":"10.1155\/2021\/7463391","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T14:35:12Z","timestamp":1637764512000},"page":"1-15","source":"Crossref","is-referenced-by-count":7,"title":["Effect of Antioxidants in the Treatment of COPD Patients: Scoping Review"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3209-3462","authenticated-orcid":true,"given":"Mauricio","family":"Orozco-Levi","sequence":"first","affiliation":[{"name":"Servicio de Neumolog\u00eda, Fundaci\u00f3n Cardiovascular de Colombia, Hospital Internacional de Colombia, Calle 155A No. 23-58 Floridablanca Santander\/Valle de Menzuly Km 7 Piedecuesta, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1847-4282","authenticated-orcid":true,"given":"Claudia","family":"Colmenares-Mej\u00eda","sequence":"additional","affiliation":[{"name":"Centro de Investigaciones Fundaci\u00f3n Cardiovascular de Colombia, Calle 155A No. 23-58 Floridablanca, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Ru\u00edz","sequence":"additional","affiliation":[{"name":"Centro de Investigaciones Fundaci\u00f3n Cardiovascular de Colombia, Calle 155A No. 23-58 Floridablanca, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurley Dayanna","family":"Valencia-Bar\u00f3n","sequence":"additional","affiliation":[{"name":"Centro de Investigaciones Fundaci\u00f3n Cardiovascular de Colombia, Calle 155A No. 23-58 Floridablanca, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7441-8798","authenticated-orcid":true,"given":"Alba","family":"Ram\u00edrez-Sarmiento","sequence":"additional","affiliation":[{"name":"Servicio de Neumolog\u00eda, Fundaci\u00f3n Cardiovascular de Colombia, Hospital Internacional de Colombia, Calle 155A No. 23-58 Floridablanca Santander\/Valle de Menzuly Km 7 Piedecuesta, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8875-0110","authenticated-orcid":true,"given":"Doris Cristina","family":"Quintero-Lesmes","sequence":"additional","affiliation":[{"name":"Centro de Investigaciones Fundaci\u00f3n Cardiovascular de Colombia, Calle 155A No. 23-58 Floridablanca, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3532-2002","authenticated-orcid":true,"given":"Norma C.","family":"Serrano","sequence":"additional","affiliation":[{"name":"Centro de Investigaciones Fundaci\u00f3n Cardiovascular de Colombia, Calle 155A No. 23-58 Floridablanca, Santander, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","volume-title":"Gu\u00eda de bolsillo para el diagn\u00f3stico, manejo y prevenci\u00f3n de la EPOC: una gu\u00eda para profesionales de la asistencia sanitaria","author":"Global Initiative for Chronic Obstructive Lung Disease (GOLD)","year":"2017"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32279-7"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32203-7"},{"key":"4","volume-title":"World Health Statistics 2008","author":"World Heatlh Organization (WHO)","year":"2008"},{"key":"5","volume-title":"Gu\u00eda de pr\u00e1ctica cl\u00ednica Basada en la evidencia para la prevenci\u00f3n, diagn\u00f3stico, tratamiento y seguimiento de la enfermedad pulmonar obstructiva cr\u00f3nica (EPOC) en poblaci\u00f3n adulta","author":"Ministerio de Salud Y Protecci\u00f3n Social, D. 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