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The lack of primary ophthalmologists in China results in the inability of basic-level hospitals to diagnose pterygium patients. To solve this problem, an intelligent-assisted lightweight pterygium diagnosis model based on anterior segment images is proposed in this study. Methods. Pterygium is a common and frequently occurring disease in ophthalmology, and fibrous tissue hyperplasia is both a diagnostic biomarker and a surgical biomarker. The model diagnosed pterygium based on biomarkers of pterygium. First, a total of 436 anterior segment images were collected; then, two intelligent-assisted lightweight pterygium diagnosis models (MobileNet 1 and MobileNet 2) based on raw data and augmented data were trained via transfer learning. The results of the lightweight models were compared with the clinical results. The classic models (AlexNet, VGG16 and ResNet18) were also used for training and testing, and their results were compared with the lightweight models. A total of 188 anterior segment images were used for testing. Sensitivity, specificity, F1-score, accuracy, kappa, area under the concentration-time curve (AUC), 95% CI, size, and parameters are the evaluation indicators in this study. Results. There are 188 anterior segment images that were used for testing the five intelligent-assisted pterygium diagnosis models. The overall evaluation index for the MobileNet2 model was the best. The sensitivity, specificity, F1-score, and AUC of the MobileNet2 model for the normal anterior segment image diagnosis were 96.72%, 98.43%, 96.72%, and 0976, respectively; for the pterygium observation period anterior segment image diagnosis, the sensitivity, specificity, F1-score, and AUC were 83.7%, 90.48%, 82.54%, and 0.872, respectively; for the surgery period anterior segment image diagnosis, the sensitivity, specificity, F1-score, and AUC were 84.62%, 93.50%, 85.94%, and 0.891, respectively. The kappa value of the MobileNet2 model was 77.64%, the accuracy was 85.11%, the model size was 13.5\u2009M, and the parameter size was 4.2\u2009M. Conclusion. This study used deep learning methods to propose a three-category intelligent lightweight-assisted pterygium diagnosis model. The developed model can be used to screen patients for pterygium problems initially, provide reasonable suggestions, and provide timely referrals. It can help primary doctors improve pterygium diagnoses, confer social benefits, and lay the foundation for future models to be embedded in mobile devices.<\/jats:p>","DOI":"10.1155\/2021\/7651462","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:50:24Z","timestamp":1627606224000},"page":"1-8","source":"Crossref","is-referenced-by-count":23,"title":["Research on an Intelligent Lightweight-Assisted Pterygium Diagnosis Model Based on Anterior Segment Images"],"prefix":"10.1155","volume":"2021","author":[{"given":"Bo","family":"Zheng","sequence":"first","affiliation":[{"name":"School of Information Engineering, Huzhou University, Huzhou 313000, China"},{"name":"Zhejiang Province Key Laboratory of Smart Management & Application of Modern Agricultural Resources, Huzhou University, Huzhou 313000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunfang","family":"Liu","sequence":"additional","affiliation":[{"name":"The First People\u2019s Hospital of Huzhou, Huzhou313000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"He","sequence":"additional","affiliation":[{"name":"School of Information Engineering, Huzhou University, Huzhou 313000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maonian","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Information Engineering, Huzhou University, Huzhou 313000, China"},{"name":"Zhejiang Province Key Laboratory of Smart Management & Application of Modern Agricultural Resources, Huzhou University, Huzhou 313000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Jin","sequence":"additional","affiliation":[{"name":"The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojun","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Information Engineering, Huzhou University, Huzhou 313000, China"},{"name":"Zhejiang Province Key Laboratory of Smart Management & Application of Modern Agricultural Resources, Huzhou University, Huzhou 313000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiulan","family":"Hao","sequence":"additional","affiliation":[{"name":"School of Information Engineering, Huzhou University, Huzhou 313000, China"},{"name":"Zhejiang Province Key Laboratory of Smart Management & Application of Modern Agricultural Resources, Huzhou University, Huzhou 313000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4478-9176","authenticated-orcid":true,"given":"Chenghu","family":"Wang","sequence":"additional","affiliation":[{"name":"The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7629-0193","authenticated-orcid":true,"given":"Weihua","family":"Yang","sequence":"additional","affiliation":[{"name":"The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"3","key":"1","first-page":"296","article-title":"Research progress of treatment techniques for pterygium","volume":"41","author":"X. 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