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Given the lower prevalence of syphilis in adolescent females, this infection was not included on the initial differential diagnosis. The evolving presentation of syphilis over time complicates the diagnosis and management of these infections, as it did for the patient in this report. The authors provide a detailed discussion of the patient\u2019s clinical findings, including the protean features of syphilis infection. This case is particularly relevant to the fields of general pediatrics and pediatric hospital medicine.<\/jats:p>","DOI":"10.1155\/2021\/7755914","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T23:35:09Z","timestamp":1629156909000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An Unusual Visit from an Old Foe: Oral Presentation of Syphilis in a Teenage Patient"],"prefix":"10.1155","volume":"2021","author":[{"given":"Bedirhan","family":"Tarhan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7811-5639","authenticated-orcid":false,"given":"Sydur","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Halloran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Sites","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avni","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8267-6885","authenticated-orcid":false,"given":"Kathleen","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maritza","family":"Plaza-Verduin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thao","family":"Vu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8,16]]},"reference":[{"key":"e_1_2_8_1_2","unstructured":"Press Release 2018 STD Prevention Conference | 2018 | Newsroom | NCHHSTP | CDC 2018.https:\/\/www.cdc.gov\/nchhstp\/newsroom\/2018\/press-release-2018-std-prevention-conference.html."},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1191\/096120301680417002"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780261218"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-209824"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/23744235.2019.1690676"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1943.00210070086008"},{"key":"e_1_2_8_7_2","article-title":"Modern clinical syphilology","volume":"67","author":"Stokes J. 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