{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:22:27Z","timestamp":1767165747866,"version":"build-2238731810"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,8,6]],"date-time":"2021-08-06T00:00:00Z","timestamp":1628208000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2021,8,6]]},"abstract":"<jats:p>Thyroid cancer has become the most common malignant tumor in the endocrine system, and its global incidence has been showing an upward trend. The diagnosis methods of thyroid cancer include ultrasound, fine-needle aspiration cytology, and neck CT, but the single ultrasound feature cannot simultaneously take into account the sensitivity and specificity of more than 85% when diagnosing thyroid cancer. The development of virtual technology can significantly improve the diagnosis of the thyroid gland. Based on this, this article proposes a clinical study of virtual reality technology combined with contrast-enhanced ultrasound in the assessment of thyroid cancer. This article uses a variety of methods, such as literature method, mathematical statistics, and experimental research, in-depth study of the theoretical cornerstones of virtual reality augmented technology, the application status of ultrasound contrast technology, and so on. And a fuzzy mean clustering algorithm was proposed to identify ultrasound images. Then, a clinical experiment of virtual reality augmented technology combined with contrast-enhanced ultrasound was designed to evaluate thyroid cancer, which included comparison of contrast-enhanced ultrasound signs, analysis of enhancement results, multifactor logistic analysis, and diagnostic efficacy analysis of ultrasound signs. The combined application of virtual reality augmented technology and contrast-enhanced ultrasound in the study of thyroid cancer has a sensitivity and specificity exceeding 85% as the diagnosis boundary changes, and the accuracy of the combined diagnosis is relatively high.<\/jats:p>","DOI":"10.1155\/2021\/8042755","type":"journal-article","created":{"date-parts":[[2021,8,6]],"date-time":"2021-08-06T17:20:10Z","timestamp":1628270410000},"page":"1-16","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Study of Virtual Reality Augmented Technology Combined with Contrast-Enhanced Ultrasound in the Assessment of Thyroid Cancer"],"prefix":"10.1155","volume":"2021","author":[{"given":"Qinghua","family":"Liu","sequence":"first","affiliation":[{"name":"Ultrasonography Department, Rizhao People\u2019s Hospital, Rizhao 276826, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Cheng","sequence":"additional","affiliation":[{"name":"Ultrasonography Department, Rizhao People\u2019s Hospital, Rizhao 276826, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8690-9300","authenticated-orcid":true,"given":"Jingjing","family":"Li","sequence":"additional","affiliation":[{"name":"Ultrasonography Department, Rizhao People\u2019s Hospital, Rizhao 276826, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4437-8438","authenticated-orcid":true,"given":"Lei","family":"Liu","sequence":"additional","affiliation":[{"name":"Ultrasonography Department, Rizhao People\u2019s Hospital, Rizhao 276826, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongbo","family":"Li","sequence":"additional","affiliation":[{"name":"General Surgery, Rizhao People\u2019s Hospital, Rizhao 276826, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"2","key":"1","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1007\/s11071-018-4421-9","article-title":"Primary resonance analysis and vibration suppression for the harmonically excited nonlinear suspension system using A pair of symmetric viscoelastic buffers","volume":"94","author":"X. 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