{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:43:24Z","timestamp":1747190604347,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T00:00:00Z","timestamp":1629936000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Neurological Medicine"],"published-print":{"date-parts":[[2021,8,26]]},"abstract":"<jats:p>Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte cell surface and on the outermost cell surface of the myelin sheath may also be present in patients with NMOSD bilateral optic neuritis. Here, we describe a case of a thirty-nine-year-old-female with recurrent bilateral optic neuritis with positive anti-MOG antibody, and anti-MOG syndrome has not previously been reported from Nepal.<\/jats:p>","DOI":"10.1155\/2021\/8100423","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T20:08:44Z","timestamp":1630094924000},"page":"1-3","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent Bilateral Optic Neuritis Associated with Myelin Oligodendrocyte Glycoprotein Antibody: A Case Report from Nepal"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8203-3329","authenticated-orcid":true,"given":"Sangam","family":"Shah","sequence":"first","affiliation":[{"name":"Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7680-7036","authenticated-orcid":true,"given":"Rajeev","family":"Ojha","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeeta","family":"Sitaula","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dosti","family":"Regmi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanti Children's Hospital, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ragesh","family":"Karn","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bikram Prasad","family":"Gajurel","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reema","family":"Rajbhandari","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niraj","family":"Gautam","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2594-2603","authenticated-orcid":true,"given":"Sunanda","family":"Paudel","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aashish","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines7020042"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458515572406"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000060"},{"key":"4","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/cen3.12107","article-title":"Evaluation of aquaporin-4 antibody assays","volume":"5","author":"P. J. Waters","year":"2014","journal-title":"Clinical and Experimental Neuroimmunology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1371179"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-018-0561-1"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2016.02.004"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000101"},{"issue":"1","key":"9","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-016-0720-6","article-title":"MOG-IgG in NMO and related disorders: A multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients","volume":"13","author":"F. Pache","year":"2016","journal-title":"Journal of Neuroinflammation"}],"container-title":["Case Reports in Neurological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crinm\/2021\/8100423.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crinm\/2021\/8100423.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crinm\/2021\/8100423.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T20:08:49Z","timestamp":1630094929000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crinm\/2021\/8100423\/"}},"subtitle":[],"editor":[{"given":"Peter","family":"Berlit","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,8,26]]},"references-count":9,"alternative-id":["8100423","8100423"],"URL":"https:\/\/doi.org\/10.1155\/2021\/8100423","relation":{},"ISSN":["2090-6676","2090-6668"],"issn-type":[{"type":"electronic","value":"2090-6676"},{"type":"print","value":"2090-6668"}],"subject":[],"published":{"date-parts":[[2021,8,26]]}}}