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This study described an unusual case of hypopituitarism in a patient who presented with general abdominal pain, abdominal tenderness, nausea, vomiting, hypotension, and hypoglycemia. At first, the patient was admitted with the diagnosis of acute cholecystitis, but after treatment of hypopituitarism and adrenal insufficiency, his symptoms resolved completely, without the need for surgery. Hypopituitarism and secondary adrenal insufficiency should be considered in the differential diagnosis of the patients who present with acute abdomen, hypotension, or hypoglycemia.<\/jats:p>","DOI":"10.1155\/2021\/8318747","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T20:05:17Z","timestamp":1638302717000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Secondary Adrenal Insufficiency Misdiagnosed as Acute Cholecystitis"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7997-6326","authenticated-orcid":false,"given":"Moslem","family":"Sedaghattalab","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9166-419X","authenticated-orcid":false,"given":"Amir Hossein","family":"Doustimotlagh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,30]]},"reference":[{"volume-title":"Cleveland Clinic: Current Clinical Medicine","year":"2010","author":"Skugo M.","key":"e_1_2_10_1_2"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2012.05.002"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(98)85043-5"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0306"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-016-0487-8"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.81.3.8772595"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0300-595x(85)80084-0"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(03)13492-7"},{"volume-title":"Harrison\u2032s Principles of Internal Medicine, 19th Eddition","year":"2015","author":"Arlt W.","key":"e_1_2_10_9_2"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1807486"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2021\/8318747.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2021\/8318747.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2021\/8318747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:05:54Z","timestamp":1762473954000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2021\/8318747"}},"subtitle":[],"editor":[{"given":"J. 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