{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:44:35Z","timestamp":1747190675929,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T00:00:00Z","timestamp":1631664000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Transplantation"],"published-print":{"date-parts":[[2021,9,15]]},"abstract":"<jats:p>Immune thrombocytopenia is a consumptive coagulopathy that can be either idiopathic or associated with infectious or autoimmune etiologies. Here, we present a case of immune thrombocytopenia in the setting of acute liver failure due to coexisting diagnoses of hepatitis B virus and autoimmune hepatitis. Our patient underwent orthotopic liver transplantation and recovered hemostatic platelet counts after treatment with romiplostim, a thrombopoietin receptor agonist, 51 days after transplantation. To our knowledge, this is the first case report of immune thrombocytopenia secondary to both hepatitis B virus and autoimmune hepatitis in a patient with acute liver failure.<\/jats:p>","DOI":"10.1155\/2021\/8484106","type":"journal-article","created":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T23:05:06Z","timestamp":1631747106000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2475-6577","authenticated-orcid":true,"given":"Chloe","family":"Nobuhara","sequence":"first","affiliation":[{"name":"Department of Surgery, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana M.","family":"Cardona","sequence":"additional","affiliation":[{"name":"Department of Pathology, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat O.","family":"Arcasoy","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl L.","family":"Berg","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3476-2313","authenticated-orcid":true,"given":"Andrew S.","family":"Barbas","sequence":"additional","affiliation":[{"name":"Department of Surgery, Duke University Medical Center, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-162503"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00880"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5305691"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.56.7506"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-009-9305-x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000966"},{"issue":"1","key":"7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1665-2681(19)30914-7","article-title":"Autoimmune hepatitis in patients with chronic HBV and HCV infections: patterns of clinical characteristics, disease progression and outcome","volume":"13","author":"E. 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