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Because of the tendency of this disease to imitate many diseases, diagnosis may be difficult on presentation. We present a case of disseminated coccidioidomycosis in a patient who was initially managed as miliary tuberculosis. In endemic areas, coccidioidomycosis is one of the two top differentials for miliary micronodular distribution on chest imaging. The patient was a recently diagnosed HIV positive patient and presented to the hospital with multiorgan failure, septic shock, and acute respiratory distress syndrome. He rapidly deteriorated and died within three days of presentation at the emergency department.<\/jats:p>","DOI":"10.1155\/2021\/8837493","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T21:22:48Z","timestamp":1618608168000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["Disseminated Coccidioidomycosis Presenting as Septic Shock with Multiorgan Failure"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2220-2765","authenticated-orcid":true,"given":"Olufemi","family":"Aduroja","sequence":"first","affiliation":[{"name":"Department of Nephrology, Texas Tech University Health Sciences Center, 2000B Transmountain Road,Suite 465, El Paso, TX 79911, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2183-7024","authenticated-orcid":true,"given":"Jerome","family":"Okudo","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Texas, 1200 Pressler Street, Houston, TX 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8382-3077","authenticated-orcid":true,"given":"Angelica","family":"Padilla","sequence":"additional","affiliation":[{"name":"Department of Pathology, Texas Tech University Health Sciences Center, 4800 Alberta Avenue, El Paso, TX 79905, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10759"},{"issue":"1","key":"2","first-page":"20","article-title":"Coccidioidomycosis diseminada con coccidioidoma gigante de la gl\u00e1ndula suprarenal","volume":"66","author":"M. 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