{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T05:28:34Z","timestamp":1754112514773,"version":"3.40.5"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2021,1,22]]},"abstract":"<jats:p>Purpose. To study the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in a tertiary eye center in Nepal. Methods. Baseline demographic details and clinical features of six patients diagnosed as VKH in a tertiary eye center were retrospectively reviewed. Examinations included best corrected visual acuity, intraocular pressure, and slit lamp examination of anterior and posterior segments. Baseline blood investigations, chest X-ray, fundus photography, and fundus fluorescent angiography (FFA) were performed on all the patients. Results. The mean age at presentation was <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>46<\/a:mn>\n                        <a:mo>\u00b1<\/a:mo>\n                        <a:mn>8.43<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula> years with female predominance (83.3%). The disease was complete in 16.7%, incomplete in 16.7%, and probable in 66.7% of the patients. Most cases presented in acute uveitis stage (66.7%). The most common finding in acute cases was serous retinal detachment (66.7%), followed by disc edema (58.3%), whereas in chronic cases, depigmented fundus was the most common. All cases had bilateral presentation. Conclusion. VKH is an important cause of bilateral loss of vision and has a good visual prognosis if aggressive treatment is initiated during the early stages.<\/jats:p>","DOI":"10.1155\/2021\/8848659","type":"journal-article","created":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T03:05:14Z","timestamp":1611457514000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0759-2032","authenticated-orcid":true,"given":"Pranav","family":"Shrestha","sequence":"first","affiliation":[{"name":"Mechi Eye Hospital, Jhapa 57200, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0550-6938","authenticated-orcid":true,"given":"Sadhana","family":"Sharma","sequence":"additional","affiliation":[{"name":"Mechi Eye Hospital, Jhapa 57200, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8624-4433","authenticated-orcid":true,"given":"Ranju","family":"Kharel","sequence":"additional","affiliation":[{"name":"Department of Uveitis, B. P. Koirala Lions Center for Ophthalmic Studies (BPKLCOS), Institute of Medicine, Maharajgunj, Kathmandu 44600, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.2147\/OPTH.S134977"},{"doi-asserted-by":"publisher","key":"2","DOI":"10.4103\/2320-3897.183722"},{"doi-asserted-by":"publisher","key":"3","DOI":"10.1097\/MD.0000000000009914"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.4103\/0974-9233.75898"},{"doi-asserted-by":"publisher","key":"5","DOI":"10.1007\/s00417-009-1068-8"},{"doi-asserted-by":"publisher","key":"6","DOI":"10.1016\/S0039-6257(05)80105-5"},{"doi-asserted-by":"publisher","key":"7","DOI":"10.1159\/000441616"},{"doi-asserted-by":"publisher","key":"8","DOI":"10.1016\/S0002-9394(14)72334-7"},{"doi-asserted-by":"publisher","key":"9","DOI":"10.1097\/00006982-199111030-00001"},{"doi-asserted-by":"publisher","key":"10","DOI":"10.1080\/09273948.2020.1833225"},{"doi-asserted-by":"publisher","key":"11","DOI":"10.1186\/1869-5760-4-6"},{"issue":"2","key":"12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1080\/09273940500536766","article-title":"Immunomodulatory therapy for Vogt-Koyanagi-Harada patients as first-line therapy","volume":"14","author":"I. 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Dogan","year":"2016","journal-title":"Springerplus"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2021\/8848659.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2021\/8848659.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2021\/8848659.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T03:05:25Z","timestamp":1611457525000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2021\/8848659\/"}},"subtitle":[],"editor":[{"given":"Nicola","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,1,22]]},"references-count":13,"alternative-id":["8848659","8848659"],"URL":"https:\/\/doi.org\/10.1155\/2021\/8848659","relation":{},"ISSN":["2090-6730","2090-6722"],"issn-type":[{"type":"electronic","value":"2090-6730"},{"type":"print","value":"2090-6722"}],"subject":[],"published":{"date-parts":[[2021,1,22]]}}}