{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:44:53Z","timestamp":1747190693790,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Urology"],"published-print":{"date-parts":[[2021,2,23]]},"abstract":"<jats:p>In this case report, we are reporting the case of a 68-year-old male patient who was admitted in our hospital for unintended weight loss, asthenia, and anorexia. Physical examination showed clinical signs of anemia such as pallor of skin and mucous membranes; hemodynamic parameters were normal. Complete blood count (CBC) analysis showed a pancytopenia with anemia, thrombocytopenia, and leukopenia. BM biopsy was performed, showing a malignant infiltration of bone marrow by a metastatic prostate cancer confirmed by immunohistochemistry. Prostate biopsy confirmed the diagnosis of acinar adenocarcinoma with Gleason score 8 (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>4<\/a:mn>\n                        <a:mo>+<\/a:mo>\n                        <a:mn>4<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>), ISUP grade group 4. Our patient underwent chemical castration using LH-RH analogs in association with second-line hormone therapy by abiraterone acetate. The evolution was good on both the oncological and hematological levels.<\/jats:p>","DOI":"10.1155\/2021\/8898130","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T02:20:23Z","timestamp":1614133223000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["Medullary Aplasia Revealing a Metastatic Prostatic Adenocarcinoma"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0595-0227","authenticated-orcid":true,"given":"Idriss","family":"Ziani","sequence":"first","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8866-815X","authenticated-orcid":true,"given":"Ahmed","family":"Ibrahimi","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Bellouki","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youssef","family":"Zaoui","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmine Laraqui","family":"Housseini","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Faculty of Medicine of Rabat, Mohammed V University, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fouad","family":"Zouidia","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Faculty of Medicine of Rabat, Mohammed V University, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hachem El","family":"Sayegh","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lounis","family":"Benslimane","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yassine","family":"Nouini","sequence":"additional","affiliation":[{"name":"Department of Urological Surgery \u201cA\u201d, Ibn Sina University Hospital of Rabat, Rabat, Morocco"},{"name":"Department of Anatomopathology and Cytology, Ibn Sina University Hospital of Rabat, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"author":"J. 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