{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T15:09:13Z","timestamp":1764601753027,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Indonesian Society of Hematology and Medical Oncology of Semarang Chapter"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2021,11,3]]},"abstract":"<jats:p>Up to 20\u201340% of patients with Hodgkin\u2019s lymphoma will eventually relapse after treatment, among which early relapse confers a poor outcome. With salvage chemotherapy followed by autologous stem cell transplantation (ASCT), the long-term remission rate is 30%. We report our experience of using a modified-BEAM conditioning regimen without BCNU consisting of etoposide, cytarabine, and melphalan (EAM) in a patient with relapsed Hodgkin\u2019s lymphoma. Before transplantation, the patient achieved second complete remission (CR2) using brentuximab vedotin and ESHAP (BR-ESHAP) chemotherapy. The ASCT went well without significant complications. This case demonstrated the considerable efficacy of EAM protocol as a conditioning regimen in terms of sufficient ablative capabilities, and the patient showed a successful hematopoietic engraftment. Although durability of the disease-free survival needs further observation, it had nearly 18 months of complete remission and the patient was in good performance status at the time of writing this manuscript.<\/jats:p>","DOI":"10.1155\/2021\/9632427","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T18:05:10Z","timestamp":1635962710000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["The Use of Etoposide, Ara-Cytarabine, and Melphalan (EAM) Conditioning Chemotherapy in Autologous Stem Cell Transplantation (ASCT) for a Patient with Relapsed Hodgkin\u2019s Lymphoma"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5003-1292","authenticated-orcid":true,"given":"Eko A.","family":"Pangarsa","sequence":"first","affiliation":[{"name":"Subdivion of Hematology and Medical Oncology, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9777-9705","authenticated-orcid":true,"given":"Ridho M.","family":"Naibaho","sequence":"additional","affiliation":[{"name":"Trainee in Hematology and Medical Oncology, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia"},{"name":"Department of Internal Medicine, Parikesit Hospital, Mulawarman School of Medicine, Samarinda, East Kalimantan, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1907-5446","authenticated-orcid":true,"given":"Vina","family":"Yunarvika","sequence":"additional","affiliation":[{"name":"Subdivion of Hematology and Medical Oncology, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8654-6746","authenticated-orcid":true,"given":"Budi","family":"Setiawan","sequence":"additional","affiliation":[{"name":"Subdivion of Hematology and Medical Oncology, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6093-5049","authenticated-orcid":true,"given":"Damai","family":"Santosa","sequence":"additional","affiliation":[{"name":"Subdivion of Hematology and Medical Oncology, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9755-893X","authenticated-orcid":true,"given":"Catharina","family":"Suharti","sequence":"additional","affiliation":[{"name":"Subdivion of Hematology and Medical Oncology, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700913"},{"key":"2","article-title":"High dose chemotherapy and stem cell transplantation in Hodgkin\u2019s disease","volume-title":"High Dose Chemotherapy: Principles and Practice","author":"J. 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