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In this study, the fungal endophyte <jats:italic>Acremonium<\/jats:italic> sp. Ld\u201003 was isolated from the bulbs of <jats:italic>L. davidii<\/jats:italic> and identified through morphological and molecular analysis. The molecular and morphological analysis confirmed the endophytic fungal strain as <jats:italic>Acremonium<\/jats:italic> sp. Ld\u201003. Antifungal effects of Ld\u201003 were observed against <jats:italic>Fusarium oxysporum<\/jats:italic>, <jats:italic>Botrytis cinerea<\/jats:italic>, <jats:italic>Botryosphaeria dothidea<\/jats:italic>, and <jats:italic>Fusarium fujikuroi<\/jats:italic>. The highest growth inhibition, i.e., 78.39 \u00b1 4.21<jats:italic>%<\/jats:italic>, was observed for <jats:italic>B. dothidea<\/jats:italic> followed by 56.68 \u00b1 4.38<jats:italic>%<\/jats:italic>, 43.62 \u00b1 3.81<jats:italic>%<\/jats:italic>, and 20.12 \u00b1 2.45<jats:italic>%<\/jats:italic> for <jats:italic>B. cinerea<\/jats:italic>, <jats:italic>F. fujikuroi<\/jats:italic>, and <jats:italic>F. oxysporum<\/jats:italic>, respectively. Analysis of the ethyl acetate fraction through UHPLC\u2010LTQ\u2010IT\u2010MS\/MS revealed putative secondary metabolites which included xanthurenic acid, valyl aspartic acid, gancidin W, peptides, and cyclic dipeptides such as valylarginine, cyclo\u2010[L\u2010(4\u2010hydroxy\u2010Pro)\u2010L\u2010leu], cyclo(Pro\u2010Phe), and (3S,6S)\u20103\u2010benzyl\u20106\u2010(4\u2010hydroxybenzyl)piperazine\u20102,5\u2010dione. Other metabolites included (S)\u20103\u2010(4\u2010hydroxyphenyl)\u20102\u2010((S)\u2010pyrrolidine\u20102\u2010carboxamido)propanoic acid, dibutyl phthalate (DBP), 9\u2010octadecenamide, D\u2010erythro\u2010C18\u2010Sphingosine, N\u2010palmitoyl sphinganine, and hydroxypalmitoyl sphinganine. The strain Ld\u201003 showed indole acetic acid (IAA) production with or without the application of exogenous tryptophan. The IAA ranged from 53.12 \u00b1 3.20\u2009<jats:italic>\u03bc<\/jats:italic>g\u2009ml<jats:sup>-1<\/jats:sup> to 167.71 \u00b1 7.12\u2009<jats:italic>\u03bc<\/jats:italic>g\u2009ml<jats:sup>-1<\/jats:sup> under different tryptophan concentrations. The strain was able to produce siderophore, and its production was significantly decreased with increasing Fe(III) citrate concentrations in the medium. The endophytic fungal strain also showed production of organic acids and phosphate solubilization activity. Plant growth\u2010promoting effects of the strain were evaluated on <jats:italic>in vitro<\/jats:italic> seedling growth of <jats:italic>Allium tuberosum<\/jats:italic>. Application of 40% culture dilution resulted in a significant increase in root and shoot length, i.e., 24.03 \u00b1 2.71\u2009mm and 37.27 \u00b1 1.86\u2009mm, respectively, compared to nontreated control plants. The fungal endophyte Ld\u201003 demonstrated the potential of conferring disease resistance and plant growth promotion. Therefore, we conclude that the isolated <jats:italic>Acremonium<\/jats:italic> sp. Ld\u201003 should be further investigated before utilization as a biocontrol agent and plant growth stimulator.<\/jats:p>","DOI":"10.1155\/2021\/9930210","type":"journal-article","created":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T19:20:08Z","timestamp":1628104808000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Characterization of Endophytic Fungi, <i>Acremonium<\/i> sp., from <i>Lilium davidii<\/i> and Analysis of Its Antifungal and Plant Growth\u2010Promoting Effects"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9319-6222","authenticated-orcid":false,"given":"Mohammad Sayyar","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0996-1513","authenticated-orcid":false,"given":"Junlian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5359-6333","authenticated-orcid":false,"given":"Iqbal","family":"Munir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1516-772X","authenticated-orcid":false,"given":"Mingfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1013-1226","authenticated-orcid":false,"given":"Yixin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8640-5716","authenticated-orcid":false,"given":"The Su","family":"Moe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2826-3120","authenticated-orcid":false,"given":"Jing","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7854-6287","authenticated-orcid":false,"given":"Xiuhai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,4]]},"reference":[{"key":"e_1_2_9_1_2","article-title":"Fungal endophytes: diversity and functional roles","volume":"182","author":"Rodriguez R. 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