{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:06:48Z","timestamp":1790633208100,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T00:00:00Z","timestamp":1618444800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2021,4,15]]},"abstract":"<jats:p>Background. Congenital toxoplasmosis is a major sequela of untreated primary maternal infection. With or without symptoms, untreated infections eventually lead to multiple neurologic complications. Despite the high Toxoplasma gondii seroprevalence in the Ethiopian population, there are no reports of newborns diagnosed and treated for congenital toxoplasmosis. Presentation of Cases. The clinical presentation, evaluation, and management of three infants with congenital toxoplasmosis are described. Two were symptomatic at birth. All three had confirmed diagnoses using Toxoplasma serologic tests. Two completed their treatment with one infant developing complications of strabismus and seizure disorder. Discussion and Conclusions. There is little experience in managing congenital toxoplasmosis in Ethiopia due to constraints in diagnostics and therapy. The description of this first such report underscores the need for risk assessment and evaluation during antenatal care to obtain favorable fetal outcomes.<\/jats:p>","DOI":"10.1155\/2021\/9934391","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T20:09:33Z","timestamp":1618517373000},"page":"1-6","source":"Crossref","is-referenced-by-count":2,"title":["A First Report on Experience in Managing Infants with Congenital Toxoplasmosis in Ethiopia: Case Reports and a Review of Evaluation and Treatment"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0699-8433","authenticated-orcid":true,"given":"Tinsae","family":"Alemayehu","sequence":"first","affiliation":[{"name":"American Medical Center, Addis Ababa, Ethiopia"},{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics and Child Health, St. Paul\u2019s Hospital Millennium Medical College, Addis Ababa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selamawit","family":"Assefa","sequence":"additional","affiliation":[{"name":"Lancet Specialized Internal Medicine and Surgical Center, Addis Ababa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7391-9419","authenticated-orcid":true,"given":"Solomie Jebessa","family":"Deribessa","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics and Child Health, St. Paul\u2019s Hospital Millennium Medical College, Addis Ababa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semienew","family":"Ambachew","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics and Child Health, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piu077"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit032"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1541\/peds.2016-386010.1542\/peds.2016-3860"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3201\/eid1610.091674"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1086\/374647"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.06.002"},{"issue":"3","key":"7","first-page":"407","article-title":"Seroprevalence and associated risk factors of Toxoplasma gondii in pregnant women attending in northwest Ethiopia","volume":"9","author":"M. 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