{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T07:46:13Z","timestamp":1749109573543,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T00:00:00Z","timestamp":1631059200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Foreign Experts\u2019 Projects","award":["GDW20163200086","GDW20173200019","GDW2017320061","JSB2017032"],"award-info":[{"award-number":["GDW20163200086","GDW20173200019","GDW2017320061","JSB2017032"]}]},{"name":"Provincial Foreign Experts Project","award":["GDW20163200086","GDW20173200019","GDW2017320061","JSB2017032"],"award-info":[{"award-number":["GDW20163200086","GDW20173200019","GDW2017320061","JSB2017032"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2021,9,8]]},"abstract":"<jats:p>The aim of this study is to investigate the effect of platelet on the improvement of deteriorated liver function after liver resection. Six patients with hepatocellular carcinoma and liver cirrhosis have received the partial hepatectomy in the institution. Their Child\u2013Pugh grade was B, and platelet count was below 7,000\/\u00b5l. After hepatectomy, 20 units of platelet transfusion were carried out, liver function and side effects were investigated after 4 weeks, and the number of platelets increased to approximately 15,000\/\u00b5l. Liver functions, such as aspartate transaminase (AST), alanine aminotransferase (ALT), cholinesterase (ChE), and prothrombin time, as well as albumin, recover to the same level as those before operation and 4 weeks after the operation. Any side effects were not recognized in all patients. Administration of platelets for cirrhotic patient with hepatectomy was carried with safety. But remarkable effect on the improvement of liver function was not recognized.<\/jats:p>","DOI":"10.1155\/2021\/9948854","type":"journal-article","created":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T20:05:05Z","timestamp":1631304305000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of the Platelet Administration for the Patients with Liver Dysfunction after Liver Resection: Preliminary Clinical Trial"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6913-6043","authenticated-orcid":true,"given":"Hui","family":"Xu","sequence":"first","affiliation":[{"name":"Institute of Regenerative Medicine and Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang 212001, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9501-5314","authenticated-orcid":true,"given":"Yu-Mei","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Regenerative Medicine and Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang 212001, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9465-1212","authenticated-orcid":true,"given":"Yongxiang","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Second Hospital of Nanjing, Nanjing 210003, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9002-3190","authenticated-orcid":true,"given":"Yun-Wen","family":"Zheng","sequence":"additional","affiliation":[{"name":"Institute of Regenerative Medicine and Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang 212001, Jiangsu, China"},{"name":"Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"},{"name":"Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, and School of Biotechnology and Heath Sciences, Wuyi University, Jiangmen 529020, Guangdong Province, China"},{"name":"Yokohama City University School of Medicine, Yokohama, Kanagawa 234-0006, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2779-1247","authenticated-orcid":true,"given":"Nobuhiro","family":"Ohkohchi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.3322\/caac.21262"},{"doi-asserted-by":"publisher","key":"2","DOI":"10.3322\/caac.21338"},{"doi-asserted-by":"publisher","key":"3","DOI":"10.1097\/sla.0000000000000858"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.1097\/sla.0b013e3182724ce8"},{"doi-asserted-by":"publisher","key":"5","DOI":"10.1097\/sla.0b013e3181b76557"},{"doi-asserted-by":"publisher","key":"6","DOI":"10.1097\/sla.0b013e31818584c7"},{"key":"7","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/SLA.0b013e318211caf8","article-title":"Platelets administration via the portal vein promotes liverregeneration in rats after 70% hepatectomy","volume":"253","author":"R. 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