{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:55:25Z","timestamp":1790110525093,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T00:00:00Z","timestamp":1633651200000},"content-version":"vor","delay-in-days":280,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Although Kawasaki disease (KD) is the most common self\u2010limited systemic vasculitis in pediatrics, the exact etiology of the disease, its association with other diseases, and pathogens is still unknown. In order to achieve a better understanding and management of the disease, documentation and reporting of atypical cases is justified, particularly with the growing number of children with inflammatory syndrome with clinical features simulating KD during the COVID\u201019 pandemic. Here, we present a case of an atypical case of KD presenting as multisystem inflammatory syndrome (MIS) during the COVID\u201019 pandemic.\n                    <jats:italic>Case Presentation<\/jats:italic>\n                    . The patient is a 7\u2010year\u2010old girl who developed fever (39\u00b0C) and erythematous multiform rash on the abdomen and along with erythema and edema on the extremities. Laboratory evaluation revealed neutrophilia and lymphopenia along with elevated C\u2010reactive protein, erythrocyte sedimentation rate, troponin, lactate dehydrogenase, ferritin, and D\u2010dimer. Although the patient did not fulfill the KD criteria, based on approved guidelines and approaches regarding atypical KD and multisystem inflammatory syndrome in children (MIS\u2010C) during the COVID\u201019 pandemic, intravenous immunoglobulin along with aspirin was administered for the patients. The patient\u2019s symptoms resolved with an uneventful postdischarge course.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . Early diagnosis and treatment of patients meeting full or partial criteria for KD are critical to preventing end\u2010organ damage and other long\u2010term complications, especially during times of public crisis and global health emergencies, such as the novel coronavirus pandemic.\n                  <\/jats:p>","DOI":"10.1155\/2021\/9950588","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T18:58:21Z","timestamp":1633892301000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during the COVID\u201019 Pandemic"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-495X","authenticated-orcid":false,"given":"Reza","family":"Shahriarirad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2827-3575","authenticated-orcid":false,"given":"Anahita","family":"Sanaei Dashti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2029-4619","authenticated-orcid":false,"given":"Shabnam","family":"Hajiani Ghotbabadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199002000-00010"},{"key":"e_1_2_9_2_2","volume-title":"Multisystem Inflammatory Syndrome in Children and Adolescents with COVID-19: Scientific 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College of Paediatrics and Child Health Guidance- COVID-19 paediatric multisystem inflammatory syndrome 2020 Royal College of Paediatrics and Child Health London UK https:\/\/www.rcpch.ac.uk\/resources\/guidance-paediatricmultisystem-inflammatory-syndrome-temporally-associatedcovid-19."},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-020-03357-1"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05128-x"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-021-01532-0"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.925813"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30402-3"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.20.0449"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/0049475520945446"},{"key":"e_1_2_9_22_2","unstructured":"New York City Department of Health and Mental Hygiene Pediatric multi-system inflammatory syndrome potentially associated with COVID New York City Department of Health and Mental Hygiene Long Island City NY USA http:\/\/www1.nyc.gov\/assets\/doh\/downloads\/pdf\/han\/alert\/2020\/covid-19-pediatric-multi-system-inflammatory-syndrome.pdf?referringSource=articleShare."},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs-139961\/v1"}],"container-title":["Case Reports in 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