{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:54:37Z","timestamp":1790628877654,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T00:00:00Z","timestamp":1643932800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Nephrology"],"published-print":{"date-parts":[[2022,2,4]]},"abstract":"<jats:p>Systemic lupus erythematosus (SLE) and ulcerative colitis (UC) are multisystem autoimmune disorders that rarely coexist. We report a case history of a 21-year-old male, presenting with bloody diarrhea and, later, diagnosed to have ulcerative colitis on colonic biopsy. There was clinically silent renal impairment leading to end-stage kidney disease requiring hemodialysis possibly secondary to ongoing lupus nephritis as suggested by positive lupus-specific antibodies\u2019 detection. Besides this, the diagnosis of lupus associated with early communicating hydrocephalus was made on CT brain findings which clinically responded well to the initiation of immunosuppressive therapy. It is imperative to keep in mind the remote possibility of ulcerative colitis in an SLE patient with gastrointestinal (GI) manifestations. Communicating hydrocephalus is a rare neurological manifestation of SLE leading to seizures and can respond well to the initiation of steroids and immunosuppressants. Therefore, a trial of immunosuppressant medications must be given even in a patient with end-stage renal disease (ESRD) to halter extra renal rare lupus manifestations.<\/jats:p>","DOI":"10.1155\/2022\/1079300","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T19:05:08Z","timestamp":1644260708000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Coexistence of Lupus Nephritis, Ulcerative Colitis, and Communicating Hydrocephalus: A Report of a 21-Year-Old Male"],"prefix":"10.1155","volume":"2022","author":[{"given":"Bushra Ali","family":"Khan","sequence":"first","affiliation":[{"name":"Shifa International Hospital, H-8\/4, Pitras Bukhari Road, Islamabad, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7139-8912","authenticated-orcid":true,"given":"Nida","family":"Saleem","sequence":"additional","affiliation":[{"name":"Shifa International Hospital, H-8\/4, Pitras Bukhari Road, Islamabad, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danyal","family":"Hassan","sequence":"additional","affiliation":[{"name":"Shifa International Hospital, H-8\/4, Pitras Bukhari Road, Islamabad, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shabaz","family":"Kiani","sequence":"additional","affiliation":[{"name":"Shifa International Hospital, H-8\/4, Pitras Bukhari Road, Islamabad, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Haneef","sequence":"additional","affiliation":[{"name":"Shifa International Hospital, H-8\/4, Pitras Bukhari Road, Islamabad, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2012.03.005"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1177\/0961203308100658"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2006.02.001"},{"key":"4","first-page":"1","article-title":"Lupus enteritis\u2014an unusual cause for acute abdominal pain","author":"M. C. Abdulla","year":"2020"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1080\/08916934.2017.1344976"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1177\/0961203317751857"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6096.1188"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21296"},{"issue":"8","key":"9","first-page":"1299","article-title":"Communicating hydrocephalus in systemic lupus erythematosus with antiphospholipid antibody syndrome","volume":"19","author":"P. R. Mortifee","year":"1992","journal-title":"Journal of Rheumatology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-014-0452-6"}],"container-title":["Case Reports in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2022\/1079300.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2022\/1079300.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2022\/1079300.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T19:05:10Z","timestamp":1644260710000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crin\/2022\/1079300\/"}},"subtitle":[],"editor":[{"given":"Sophia","family":"Lionaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,2,4]]},"references-count":10,"alternative-id":["1079300","1079300"],"URL":"https:\/\/doi.org\/10.1155\/2022\/1079300","relation":{},"ISSN":["2090-665X","2090-6641"],"issn-type":[{"value":"2090-665X","type":"electronic"},{"value":"2090-6641","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2,4]]}}}