{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:52:20Z","timestamp":1767167540675,"version":"build-2238731810"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":215,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>For the treatment of trichomonas vaginitis, a combination therapy of metronidazole vaginal effervescent tablet combined with Flavescentis Sophora suppository is proposed. The patients diagnosed with trichomonas vaginitis are divided into the conventional treatment group and the joint group. The conventional group is treated with metronidazole vaginal effervescent tablets, and the joint group is treated with metronidazole vaginal effervescent tablets combined with sophora bolt. Both groups are treated for 3 months to observe the therapeutic effect of the two treatment methods. The expressions of IL\u20102 and IL\u201013 in serum of patients are detected by the ELISA. The changes in the vaginal pH value and cleanliness at each time point are observed. The patients are followed up for 6\u2009months after treatment in order to observe the recurrence of trichomonas vaginitis in both groups. Experimental results show that the combination of the two tablets can further improve the clinical efficacy and reduce the inflammatory response and effectively improve the PH value and cleanliness of the vagina, and the recurrence rate is lower, which is worthy of clinical application.<\/jats:p>","DOI":"10.1155\/2022\/1250755","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T14:20:32Z","timestamp":1659622832000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["[Retracted] Clinical Effect of Metronidazole Vaginal Effervescent Tablet Combined with Flavescentis Sophora Suppository in the Treatment of Trichomonas Vaginitis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1862-7285","authenticated-orcid":false,"given":"Lingjia","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"e_1_2_10_1_2","first-page":"7148","article-title":"Associations between bacterial vaginosis, candida vaginitis, trichomonas vaginalis, and vaginal pathogenic community in Chinese women","volume":"13","author":"Yuan D.","year":"2021","journal-title":"American Journal of Tourism Research"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(20)30734-9"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9091864"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.01643-19"},{"key":"e_1_2_10_5_2","first-page":"129","article-title":"Comparison of the efficacy of metronidazole supposal and metronidazole vaginal effervescent tablets in the treatment of vaginitis","volume":"19","author":"Tang J.","year":"2018","journal-title":"Journal of Contemporary Medicine"},{"key":"e_1_2_10_6_2","first-page":"2656","article-title":"Effect of matrinesuppositron combined with gynecological ozone therapy in the treatment of trichomonas vaginitis","volume":"34","author":"Jin L.","year":"2012","journal-title":"Hebei medicine"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2021.01.011"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31885"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.200192"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.8b00346"},{"key":"e_1_2_10_11_2","first-page":"23","article-title":"Comparison of clinical efficacy of metronidazole suppository and metronidazole vaginal effervescent tablets in treatment of vaginitis","volume":"50","author":"Gong H.","year":"2019","journal-title":"Journal of Heilongjiang Traditional Chinese Medicine"},{"key":"e_1_2_10_12_2","article-title":"Comparison between metronidazole hydrochloride and metronidazole effervescent tablets in the treatment of vaginitis","volume":"23","author":"Liu Z.","year":"2020","journal-title":"Health Science"},{"key":"e_1_2_10_13_2","article-title":"Comparison of efficacy of metronidazole supposate and metronidazole vaginal effervescent tablets in treatment of vaginitis","volume":"22","author":"Zhang R.","year":"2010","journal-title":"North China national defense medicine"},{"key":"e_1_2_10_14_2","article-title":"Preparation of compound sophoraflavescens supposals","volume":"14","author":"Ma P. 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