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The major difference between other related approaches is that the paper uses the multilayer neural network in the system and the neural network is online computing in the whole process. Firstly, the paper establishes the quadrotor dynamic model and introduces the conception of Sigma\u2010Pi neural network. Then, the paper adds the neural network to the attitude and trajectory tracking control loop. Moreover, the paper designs the adaptive neural network control law. At last, to illustrate the stability of the adaptive control law, the paper gives the Lyapunov stability analysis. Finally, to demonstrate the effectiveness of the method, the paper gives different types of simulation. Comparing with different cases, when increasing the layer of the neural network, the trajectory tracking performance becomes better. 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