{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T03:50:12Z","timestamp":1772164212276,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T00:00:00Z","timestamp":1649462400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universit\u00e9 Evang\u00e9lique en Afrique","award":["2020-610-CD"],"award-info":[{"award-number":["2020-610-CD"]}]},{"name":"German Institute for Medical Mission","award":["2020-610-CD"],"award-info":[{"award-number":["2020-610-CD"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[2022,4,9]]},"abstract":"<jats:p>The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with clinical manifestation cases that are almost similar to those of common respiratory viral infections. This study determined the prevalence of SARS-CoV-2 and other acute respiratory viruses among patients with flu-like symptoms in Bukavu city, Democratic Republic of Congo. We screened 1352 individuals with flu-like illnesses seeking treatment in 10 health facilities. Nasopharyngeal swab specimens were collected to detect SARS-CoV-2 using real-time reverse transcription-polymerase chain reaction (RT-PCR), and 10 common respiratory viruses were detected by multiplex reverse transcription-polymerase chain reaction assay. Overall, 13.9% (188\/1352) of patients were confirmed positive for SARS-CoV-2. Influenza A 5.6% (56\/1352) and Influenza B 0.9% (12\/1352) were the most common respiratory viruses detected. Overall, more than two cases of the other acute respiratory viruses were detected. Frequently observed symptoms associated with SARS-CoV-2 positivity were shivering (47.8%; OR\u2009=\u20091.8; CI: 0.88\u20131.35), cough (89.6%; OR\u2009=\u20096.5, CI: 2.16\u201328.2), and myalgia and dizziness (59.7%; OR\u2009=\u20092.7; CI: 1.36\u20135.85). Moreover, coinfection was observed in 12 (11.5%) specimens. SARS-CoV-2 and influenza A were the most cooccurring infections, accounting for 33.3% of all positive cases. This study demonstrates cases of COVID-19 infections cooccurring with other acute respiratory infections in Bukavu city during the ongoing outbreak of COVID-19. Therefore, testing for respiratory viruses should be performed in all patients with flu-like symptoms for effective surveillance of the transmission patterns in the COVID-19 affected areas for optimal treatment and effective disease management.<\/jats:p>","DOI":"10.1155\/2022\/1553266","type":"journal-article","created":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T22:05:08Z","timestamp":1649541908000},"page":"1-9","source":"Crossref","is-referenced-by-count":7,"title":["Molecular Evidence of Coinfection with Acute Respiratory Viruses and High Prevalence of SARS-CoV-2 among Patients Presenting Flu-Like Illness in Bukavu City, Democratic Republic of Congo"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4020-2411","authenticated-orcid":true,"given":"Patrick Bisimwa","family":"Ntagereka","sequence":"first","affiliation":[{"name":"Molecular Biology Laboratory, Universit\u00e9 Evang\u00e9lique en Afrique, Bukavu, 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