{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:10:08Z","timestamp":1767168608709,"version":"build-2238731810"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,1,12]]},"abstract":"\n Objective. To explore the effects of modified Wenjing decoction combined with online publicity and education on the treatment of primary dysmenorrhea of cold coagulation and blood stasis. Methods. The materials of 111 patients with primary dysmenorrhea of cold coagulation and blood stasis in the outpatient department (January 2019\u2013June 2021) were collected to conduct the retrospective study. The 111 patients were randomized into treatment group (n\u2009=\u200959) and control group (n\u2009=\u200952). The control group received online publicity and education and conventional treatment, and the treatment group received online publicity and education and modified Wenjing decoction. The patients in the two groups were continuously treated for three menstrual cycles. The treatment effects, the dosage of analgesics, the scores of associated symptoms before and after treatment, and other indexes were compared between the two groups. Results. The differences in the efficacy on abdominal pain were statistically significant between the two groups\n \n \n \n \n P<\/a:mi>\n <<\/a:mo>\n 0.05<\/a:mn>\n <\/a:mrow>\n <\/a:mfenced>\n <\/a:math>\n <\/jats:inline-formula>\n . Compared with the control group, the treatment group had lower scores of associated symptoms after treatment\n \n \n \n \n p<\/f:mi>\n <<\/f:mo>\n 0.5<\/f:mn>\n <\/f:mrow>\n <\/f:mfenced>\n <\/f:math>\n <\/jats:inline-formula>\n . After the treatment of three menstrual cycles, 54 patients in the treatment group stopped taking ibuprofen, and the average ibuprofen dosage of the other 5 patients was (0.24\u2009\u00b1\u20090.16)g. The 52 patients in the control group still needed to take ibuprofen, and the mean dosage was (0.51\u2009\u00b1\u20090.05)g. The differences in the ibuprofen dosage between the two groups had remarkable difference\n \n \n \n \n P<\/k:mi>\n <<\/k:mo>\n 0.001<\/k:mn>\n <\/k:mrow>\n <\/k:mfenced>\n <\/k:math>\n <\/jats:inline-formula>\n . Conclusion. Modified Wenjing decoction combined with online publicity and education can obviously improve the clinical symptoms of the patients with primary dysmenorrhea of cold coagulation and blood stasis and reduce the dosage of analgesics. It is worth promoting and applying in practice.\n <\/jats:p>","DOI":"10.1155\/2022\/1899356","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T14:50:09Z","timestamp":1641999009000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Modified Wenjing Decoction Combined with Online Publicity and Education on the Treatment of Primary Dysmenorrhea of Cold Coagulation and Blood Stasis"],"prefix":"10.1155","volume":"2022","author":[{"given":"Na","family":"Li","sequence":"first","affiliation":[{"name":"Department of Traditional Chinese Medicine, People\u2019s Hospital of Jinan, Jinan 271100, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Imagine, People\u2019s Hospital of Jinan, Jinan 271100, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4460-129X","authenticated-orcid":true,"given":"Pengpeng","family":"Gai","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, Zibo Central Hospital, Zibo 255000, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-021-01532-w"},{"issue":"3","key":"2","first-page":"29","article-title":"Research progress in the treatment of primary dysmenorrhea with traditional Chinese medicine","volume":"11","author":"Y. Lei","year":"2021","journal-title":"Chinese Medical Sciences"},{"key":"3","volume-title":"Chinese Medicine Gynecology","author":"J. Qian","year":"2013"},{"key":"4","volume-title":"Chinese Obstetrics and Gynecology","author":"Z. Cao","year":"2014"},{"key":"5","volume-title":"Guiding Principles for Clinical Research of New TCM Drugs","author":"X. Zheng","year":"2002"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.13702\/j.1000-0607.200618"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2010.01657.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu205"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.6224\/JN.63.4.60"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-021-03355-6"},{"issue":"23","key":"11","first-page":"144","article-title":"Research overview of the chemical constituents and pharmacological effects of Yanhusuo","volume":"10","author":"Y. Tang","year":"2018","journal-title":"Clinical Research of Traditional Chinese Medicine"},{"issue":"1","key":"12","first-page":"102","article-title":"Research progress on the chemical constituents and pharmacological activities of safflower","volume":"44","author":"X. Li","year":"2021","journal-title":"Journal of Chengdu University of Traditional Chinese Medicine"},{"issue":"12","key":"13","first-page":"2189","article-title":"Research progress of miscarriage prevention of Eucommia ulmoides Oliv","volume":"13","author":"L. Xiao","year":"2020","journal-title":"Global Traditional Chinese Medicine"},{"issue":"5","key":"14","first-page":"226","article-title":"Reasearch progress of asperosaponin VI","volume":"24","author":"H. 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