{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T20:20:50Z","timestamp":1789676450059,"version":"4.0.1"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T00:00:00Z","timestamp":1642377600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,1,17]]},"abstract":"<jats:p>The study aims to explore the effect of subclinical diabetic peripheral vascular disease and an epidemiological investigation of colour Doppler ultrasound images based on a logistic regression mathematical model and a medical image registration algorithm. Subclinical diabetes patients were selected as subjects, and after ultrasound colour Doppler ultrasonography of peripheral blood vessels, ultrasound images were taken. The experimental results show that the area under the curve (AUC) predicted by the model was 0.748, the sensitivity was 94.12%, and the specificity was 67.93%. All \u0394 were smaller than a single pixel. The detection rate of colour Doppler ultrasonography was 82.6%, which was significantly better than that of clinical examination (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.01<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). The age, course of disease, SBP, low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglyceride (TG) of the peripheral vascular disease group were significantly different from those of the no peripheral vascular disease group (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). The incidence of peripheral vascular diseases and nonperipheral vascular diseases in male patients was remarkably higher than that in female patients (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). Moreover, with the increase of age, the incidence of peripheral vascular disease and nonperipheral vascular disease in diabetic patients showed a trend of gradual increase (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). In summary, the mathematical model and registration method have high accuracy for medical image registration of patients with the diabetes epidemic. In addition, the age, course of disease, SBP, LDL-C, TG, and TC of diabetic patients were significantly different from those of normal people, which can provide a reference for the development of later diabetes epidemiology.<\/jats:p>","DOI":"10.1155\/2022\/2116224","type":"journal-article","created":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T19:20:19Z","timestamp":1642447219000},"page":"1-8","source":"Crossref","is-referenced-by-count":3,"title":["Subclinical Diabetic Peripheral Vascular Disease and Epidemiology Using Logistic Regression Mathematical Model and Medical Image Registration Algorithm"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6111-4202","authenticated-orcid":true,"given":"Nailong","family":"Jia","sequence":"first","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4176-3138","authenticated-orcid":true,"given":"Long","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5262-3603","authenticated-orcid":true,"given":"Chuizhi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7396-6293","authenticated-orcid":true,"given":"Qimao","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5583-1176","authenticated-orcid":true,"given":"Yan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1865-817X","authenticated-orcid":true,"given":"Changkun","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8055-2531","authenticated-orcid":true,"given":"Yupeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Second Affiliated Hospital of Hainan Medical College, Haikou 570311, Hainan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4956004"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1109\/42.938252"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1049\/iet-ipr.2015.0346"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijleo.2015.09.199"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1166\/jmihi.2017.2128"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1080\/2150704x.2018.1458343"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1109\/tmi.2016.2576360"},{"issue":"12","key":"8","first-page":"1679","article-title":"A robust and accurate non-rigid medical image registration algorithm based on multi-level deformable model","volume":"46","author":"Y. 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