{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:02:32Z","timestamp":1767168152299,"version":"build-2238731810"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,2,11]]},"abstract":"<jats:p>Objective. Insulin replacement therapy is the main treatment method for type 1 diabetes, and adjuvant comprehensive treatment to reduce the complications of diabetes is still the focus of research. The purpose of this study is to explore the clinical efficacy of Tresiba combined with Ingredient Rehmannia Pill in the treatment of type 1 diabetes. Methods. A total of 216 patients with type 2 diabetes admitted to our hospital from January 2019 to July 2019 were enrolled in this study. Patients in the control and observation groups were treated with Tresiba and Tresiba combined with Ingredient Rehmannia Pill, respectively. The change of TCM symptom score, blood glucose level and fasting insulin level before and after treatment were evaluated, and the insulin resistance index was calculated to observe the adverse reactions of patients. Results. After treatment, the TCM syndrome scores of the two groups decreased significantly, and the TCM syndrome scores of the observation group were significantly lower than those of the control group. The fasting blood glucose, 2\u2009h postprandial blood glucose and insulin resistance index of the observation group were lower than those of the control group. The levels of FBG, 2\u2009hBG and HbA1C in the observation group were significantly lower than those in the control group. The total effective rate of the observation group was 91.7%, which was significantly higher than that of the control group (77.1%). The adverse reactions of patients in the observation group were slightly more than those in the control group. Conclusion. Our study demonstrated that Ingredient Rehmannia Pill combined with Tresiba is effective in the treatment of type 2 diabetes, providing alternative therapies for the treatment of diabetes.<\/jats:p>","DOI":"10.1155\/2022\/2177176","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T17:50:07Z","timestamp":1644601807000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of Tresiba Combined with Six Ingredient Rehmannia Pill in the Treatment of Type 2 Diabetes"],"prefix":"10.1155","volume":"2022","author":[{"given":"Jun","family":"Li","sequence":"first","affiliation":[{"name":"Department of Emergency, Xi\u2019an No. 3 Hospital, Xi\u2019an 710018, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7952-9497","authenticated-orcid":true,"given":"Qingzhen","family":"He","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Xi\u2019an Gaoxin Hospital, Xi\u2019an 710075, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-020-01299-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12216"},{"key":"3","volume-title":"International Diabetes Federation","author":"I International Diabetes Federation","year":"2013","edition":"6th"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cppeds.2012.07.002"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016587"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-013-0051-1"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-013-0051-1"},{"issue":"6","key":"8","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s11892-012-0318-z","article-title":"Design of non-standard insulin analogs for the treatment of diabetes mellitus","volume":"12","author":"V. 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