{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:45:58Z","timestamp":1747190758867,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2022,12,27]]},"abstract":"<jats:p>Whereas typical Crohn\u2019s disease is confined to the terminal ileum and presents with abdominal pain and diarrhea, gastroduodenal manifestations of Crohn\u2019s disease are rare, with often asymptomatic patient presentations and inconclusive diagnostic testing. It is, however, a more severe form of Crohn\u2019s disease and thus warrants treatment with steroids and biologics much earlier than its ileocolonic counterpart. We present the case of a young, otherwise healthy, male with newly diagnosed ileocolonic Crohn\u2019s disease with concurrent gastroduodenal involvement that initially failed management with biologic agents. We discuss the clinical manifestations and often obscure pathology of gastroduodenal Crohn\u2019s disease and highlight the necessity of performing a concurrent esophagogastroduodenoscopic evaluation on newly diagnosed ileocolonic Crohn\u2019s disease to assess the presence of upper gastrointestinal involvement.<\/jats:p>","DOI":"10.1155\/2022\/2200438","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T23:20:06Z","timestamp":1672183206000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["An Obscure Presence of Gastroduodenal Involvement in a Newly Diagnosed Ileocolonic Crohn\u2019s Disease Patient"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4119-0053","authenticated-orcid":true,"given":"Clive Jude","family":"Miranda","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, University at Buffalo, 955 Main Street, Buffalo 14203, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murad Hayatt","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University at Buffalo, 955 Main Street, Buffalo 14203, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muddasir","family":"Ayaz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University at Buffalo, 955 Main Street, Buffalo 14203, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef","family":"Soofi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University at Buffalo, 955 Main Street, Buffalo 14203, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas Christopher","family":"Mahl","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University at Buffalo, 955 Main Street, Buffalo 14203, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"11","key":"1","first-page":"704","article-title":"Update on the incidence and prevalence of inflammatory bowel disease in the United States","volume":"12","author":"E. V. Loftus","year":"2016","journal-title":"Gastroenterology and Hepatology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.09.001"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2009.12.003"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-6109(05)70276-0"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2010.10.001"},{"key":"6","first-page":"881","article-title":"Regional jejunitis","volume":"38","author":"C. Gottlieb","year":"1937","journal-title":"American Journal of Roentgenology"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v10.i2.35"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2014.12.1.66"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-9585-3"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v3.i6.97"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255893"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2072-0"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-312581"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13880"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw168"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/610767"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.11771756284819856865"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1602773"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.651415"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v3.i6.479"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-017-0759-7"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2003.11927896"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-28032014000400003"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v112.pm9041230"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04969.x"}],"container-title":["Case Reports in Gastrointestinal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2022\/2200438.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2022\/2200438.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2022\/2200438.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T14:57:19Z","timestamp":1684594639000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crigm\/2022\/2200438\/"}},"subtitle":[],"editor":[{"given":"Hirotada","family":"Akiho","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,12,27]]},"references-count":25,"alternative-id":["2200438","2200438"],"URL":"https:\/\/doi.org\/10.1155\/2022\/2200438","relation":{},"ISSN":["2090-6536","2090-6528"],"issn-type":[{"type":"electronic","value":"2090-6536"},{"type":"print","value":"2090-6528"}],"subject":[],"published":{"date-parts":[[2022,12,27]]}}}