{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:36:50Z","timestamp":1778333810115,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,12,7]]},"abstract":"<jats:p>Background. Surgical resection with clear surgical cut margins is the mainstay of managing malignant breast neoplasms. Multiple techniques have been suggested to enhance resection status during breast-conserving surgery (BCS), including intraoperative ultrasonography (IOUS). Herein, we conducted the current investigation to reveal the benefit of IOUS on the achievement of R0 resection. Patients and Methods. This retrospective investigation included 140 patients who underwent BCS. They were divided into two groups: the IOUS group (40 cases) and the control group (100 cases). Our primary objective was to determine the free resection margin status (R0). Results. Both study groups expressed statistically comparable demographic and clinical data. Additionally, histopathological examination revealed no significant difference between the two groups regarding the tumor type, stage, or grade. Nonetheless, the R0 resection margin was more frequently encountered in association with IOUS application (97.5% compared to 79% in the control group), and that difference was statistically significant (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.007<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Conclusion. The application of IOUS has a significant beneficial impact on the outcomes of BCS. It is associated with a marked decline in positive resection margins, and its application should be encouraged in the breast oncological practice.<\/jats:p>","DOI":"10.1155\/2022\/2268821","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T17:50:06Z","timestamp":1670435406000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["The Beneficial Impact of Intraoperative Ultrasound on Resection Margin Status during Breast Conserving Surgery"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3683-2584","authenticated-orcid":true,"given":"Osama","family":"Almezaien","sequence":"first","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5337-3220","authenticated-orcid":true,"given":"Ahmed","family":"Mohamed Eldeeb","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6927-223X","authenticated-orcid":true,"given":"Abdelfattah","family":"Kalmoush","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4171-642X","authenticated-orcid":true,"given":"Mohamed","family":"Shaaban Nassar","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1523-6214","authenticated-orcid":true,"given":"Tarek","family":"Zaghlol Mohamed","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7849-3069","authenticated-orcid":true,"given":"Mohamed","family":"Sobhy Shaaban","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4871-0995","authenticated-orcid":true,"given":"Mohamed","family":"Ibrahim Henish","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0838-1082","authenticated-orcid":true,"given":"Sobhy","family":"Teama","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6681-0063","authenticated-orcid":true,"given":"Saed","family":"Abdolmonem Elgohary Khalafallah","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5494-3598","authenticated-orcid":true,"given":"Lofty A.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/437971"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2017.02.009"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2017(04)09"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000025880"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1075-122X.2006.00271.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.03.005"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-008-9929-0"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.14063"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-021-10454-8"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2016.12.012"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.11.004"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2011.08.127"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074028"},{"issue":"3","key":"14","first-page":"1051","article-title":"Intraoperative ultrasound: improved resection rates in breast-conserving surgery","volume":"32","author":"C. 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