{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:40:01Z","timestamp":1788201601494,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T00:00:00Z","timestamp":1665792000000},"content-version":"vor","delay-in-days":287,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Institute of Medical Research and Medicinal Plants Studies (IMPM) of the Ministry of Scientific Research and Innovation"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>The global malaria morbidity and mortality witnessed an increase from 2019 to 2020 partly due to disruptions in control programs\u2019 activities imposed by the COVID\u201019 pandemic. Therefore, there is still a significant burden of malaria in Cameroon which needs attention from all fronts to attain elimination goals. It is normally expected that a typical forest ecology that has undergone urbanization and subjected to high rates of ecological instabilities should also have a shift from characteristic perennial malaria transmission and a shift in the type of malaria endemicity plaguing such distorted forest ecology. In this observational comparative study, we randomly enrolled participants from rural and urban settings of a forest zone during a low malaria transmission period, which coincided with the onset of COVID\u201019 pandemic. An optimized structured questionnaire was employed, to collect socio\u2010demographic data and associated risk factors. The CareStart\u2122 Malaria HRP2 antigen test was performed on participants from both settings to determine the prevalence of community asymptomatic malaria. Of 307 participants, 188 (61.0%) were from the rural, while 119 (38.8%) from the urban community. The overall prevalence of asymptomatic malaria (27.0%) detected <jats:italic>Plasmodium falciparum<\/jats:italic> antigen in 83 participants. The urban community\u2019s prevalence was 4.2% (5 positives) while the rural community\u2019s was 41.5% (78 positives). In simple logistic regression models, rural forest community and farm around the house were statistically significant predictors of testing positive (coefficient 2.8, 95% CI 1.8\u20103.7, <jats:italic>p<\/jats:italic> value&lt;0.001) and (coefficient 3.1, 95% CI 1.1\u20105.1, <jats:italic>p<\/jats:italic> value\u2009=0.003), respectively. In the multivariate model, the strongest predictor of testing positive was living in a rural community, with <jats:italic>p<\/jats:italic> &lt; 0.001 and odds ratio of 10.9 (95% CI, 3.8\u201031.8). These results indicate that during a low transmission period, the prevalence of asymptomatic malaria differs between depleted urban and rural forested settings, suggesting a need for strategic target intervention for the control of asymptomatic malaria.<\/jats:p>","DOI":"10.1155\/2022\/2545830","type":"journal-article","created":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T16:35:06Z","timestamp":1665851706000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A Comparative Study of Asymptomatic Malaria in a Forest Rural and Depleted Forest Urban Setting during a Low Malaria Transmission and COVID\u201019 Pandemic Period"],"prefix":"10.1155","volume":"2022","author":[{"given":"Clarisse E.","family":"Mbah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9695-7645","authenticated-orcid":false,"given":"Lum A.","family":"Ambe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adela","family":"Ngwewondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvis B.","family":"Kidzeru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilian","family":"Akwah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celestin","family":"Mountchissi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamadou","family":"Mansour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward N.","family":"Sahfe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene\u00b4","family":"Kamgang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Nkengazong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,15]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.30875\/6c551ba0-en"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-265"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1179\/136485906X91512"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-8261-0"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585-39.2.350"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1070656"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2004.1590"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-12-275"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(03)90022-8"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(03)90059-9"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12038-014-9451-y"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/303269"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123630"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-29"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1586\/eri.13.45"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-9-96"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-7363-3"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parepi.2016.03.001"},{"key":"e_1_2_10_20_2","unstructured":"MesminT. 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