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Gastrodin, one of the active components of Gastrodia elata, has been used in the treatment of migraine, epilepsy, Parkinson\u2019s disease, dementia, and depression in recent years. It can improve cognitive function and related neuropsychiatric symptoms through various effects and is considered as a promising treatment for dementia. Vascular dementia is a kind of severe cognitive impairment syndrome caused by vascular factors, and it is the dementia syndrome with the largest number of patients besides Alzheimer\u2019s disease. Although there is still a lack of evidence-based explorations, the paper reviewed the mechanism and methods of gastrodin in the treatment of vascular dementia, providing a reference for clinical therapy.<\/jats:p>","DOI":"10.1155\/2022\/2563934","type":"journal-article","created":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T18:04:15Z","timestamp":1649786655000},"page":"1-13","source":"Crossref","is-referenced-by-count":19,"title":["Gastrodin and Vascular Dementia: Advances and Current Perspectives"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4422-552X","authenticated-orcid":true,"given":"Chujun","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai 200233, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4385-3543","authenticated-orcid":true,"given":"Huize","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai 200233, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9922-0446","authenticated-orcid":true,"given":"Zeyu","family":"Meng","sequence":"additional","affiliation":[{"name":"The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin 150040, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6521-8375","authenticated-orcid":true,"given":"Shengxi","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai 200233, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"3","key":"1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jalz.2017.09.007","article-title":"Progress toward standardized diagnosis of vascular cognitive impairment: guidelines from the vascular impairment of cognition classification consensus study","volume":"14","author":"O. 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