{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:30:13Z","timestamp":1762432213310,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Cardiology"],"published-print":{"date-parts":[[2022,3,15]]},"abstract":"<jats:p>Background. Cancer and ischemic stroke are associated with significant morbidity and mortality. Hypercoagulability, disseminated intravascular coagulation, venous-to-arterial embolism, and non-bacterial thrombotic endocarditis are among recognized mechanisms. Emboli to the brain, or to other organs, are known to occur as a consequence of liberated thrombotic debris originating from the thrombogenic surface of intracardiac neoplastic entities. The most common primary malignancy of the heart is sarcoma; however, masses that occur in the heart are 20 to 40 times more likely as a consequence of metastasis from other sites. Case Report. A 67-year-old woman presented to the emergency room with two brief episodes of dizziness and diplopia for 2 minutes. She had a medical history of provoked upper extremity DVT after a fracture, hypothyroidism, hyperlipidemia, and soft tissue sarcoma. The sarcoma was initially diagnosed in, and subsequently resected from, the right triceps muscle. During posttreatment surveillance, a second lesion was discovered in the left upper pulmonary lobe, and this was also completely resected 9 months following initial diagnosis. We present a case of a woman with a tertiary (cardiac) site sarcoma that presented with embolic stroke. Conclusion. Our case highlights the benefits of multimodality imaging, heart-team approach with oncology support to define anatomy, thereby enable surgical treatment, of a complex intracardiac lesion.<\/jats:p>","DOI":"10.1155\/2022\/2749303","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T23:35:13Z","timestamp":1647387313000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Multimodality Imaging for the Evaluation of an Undifferentiated Pleomorphic Sarcoma Presenting as Cardioembolic Stroke"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3482-5927","authenticated-orcid":true,"given":"Ricardo O.","family":"Esc\u00e1rcega","sequence":"first","affiliation":[{"name":"Florida Heart Associates and Heart and Vascular Institute, Lee Health System, Fort Myers, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Bailey","sequence":"additional","affiliation":[{"name":"Florida Heart Associates and Heart and Vascular Institute, Lee Health System, Fort Myers, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"DeFrain","sequence":"additional","affiliation":[{"name":"Shipley Cardiothoracic Center, Lee Health System, Fort Myers, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"2","key":"1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0733-8619(05)70195-X","article-title":"Stroke prevention: cardiac and carotid-related stroke","volume":"18","author":"T. H. Wein","year":"2000","journal-title":"Neurologic Clinics"},{"issue":"1","key":"2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2143\/AC.65.1.2045899","article-title":"Stroke and recurrent peripheral embolism in left atrial myxoma","volume":"65","author":"A. Uner","year":"2010","journal-title":"Acta Cardiologica"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.07.025"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000211"},{"issue":"1","key":"5","first-page":"1039","article-title":"Stroke and cancer- a complicated relationship","volume":"2","author":"J. L. Dearborn","year":"2014","journal-title":"Journal of Neurology & Translational Neuroscience"},{"issue":"14","key":"6","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.2169\/internalmedicine.50.5071","article-title":"A case of stroke due to tumor emboli associated with metastatic cardiac liposarcoma","volume":"50","author":"M. Mitomi","year":"2011","journal-title":"Internal Medicine"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2009.172"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.14182"},{"issue":"204-212, article e207","key":"9","article-title":"Neoplastic embolization to systemic and pulmonary arteries","volume":"68","author":"M. C. Bois","year":"2018","journal-title":"Journal of Vascular Surgery"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3233\/CBM-170448"},{"issue":"11","key":"11","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1200\/JCO.1986.4.11.1662","article-title":"Cardiac metastases from soft-tissue sarcomas","volume":"4","author":"D. E. Hallahan","year":"1986","journal-title":"Journal of Clinical Oncology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2012.06.008"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyq246"},{"issue":"2","key":"14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/1097-0142(196808)22:2<457::AID-CNCR2820220225>3.0.CO;2-E","article-title":"Metastatic disease to the heart","volume":"22","author":"G. E. Malaret","year":"1968","journal-title":"Cancer"},{"issue":"12","key":"15","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1177\/000331979504601205","article-title":"Transesophageal echocardiographic evaluation of left main coronary artery","volume":"46","author":"M. Alam","year":"1995","journal-title":"Angiology"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpradiol.2010.07.002"},{"issue":"7","key":"17","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1007\/s00595-006-3217-6","article-title":"Surgical experience of cardiac tumors: early and late results","volume":"36","author":"N. Kajihara","year":"2006","journal-title":"Surgery Today"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2011.07.027"}],"container-title":["Case Reports in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cric\/2022\/2749303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cric\/2022\/2749303.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cric\/2022\/2749303.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T23:35:23Z","timestamp":1647387323000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cric\/2022\/2749303\/"}},"subtitle":[],"editor":[{"given":"Kathleen","family":"Ngu","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,3,15]]},"references-count":18,"alternative-id":["2749303","2749303"],"URL":"https:\/\/doi.org\/10.1155\/2022\/2749303","relation":{},"ISSN":["2090-6412","2090-6404"],"issn-type":[{"type":"electronic","value":"2090-6412"},{"type":"print","value":"2090-6404"}],"subject":[],"published":{"date-parts":[[2022,3,15]]}}}