{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:21:47Z","timestamp":1767165707058,"version":"build-2238731810"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T00:00:00Z","timestamp":1647388800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2022,3,16]]},"abstract":"\n In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups randomly, 68 cases in each group. The western medicine group was treated with mosapril citrate tablets, and the combined group was treated with Shenqu xiaoshi oral liquid on the basis of the western medicine group. The efficacy of patients was evaluated 14\u2009days after treatment, and the safety, symptom score, and serum cytokines of the two groups were compared. The results showed that, after 14\u2009days of treatment, the scores of abdominal distension and abdominal pain (ADAP), lack of food (LOF), nausea and vomiting (NAV), irregular stool (IS), and mental fatigue (MF) in the combined group were all lower than those in the western group (\n \n \n P<\/a:mi>\n <<\/a:mo>\n 0.05<\/a:mn>\n <\/a:math>\n <\/jats:inline-formula>\n ). There was no statistical significance in the incidence of diarrhea, abnormal liver and kidney, and allergic rash between the two groups (\n \n \n p<\/c:mi>\n ><\/c:mo>\n 0.05<\/c:mn>\n <\/c:math>\n <\/jats:inline-formula>\n ). In conclusion, mosapride citrate tablets combined with Shenqu Xiaoshi oral liquid can achieve good therapeutic effects in children with functional dyspepsia, reduce symptom scores, improve serum cytokine levels, and have high drug safety, which is worthy of promotion and application.\n <\/jats:p>","DOI":"10.1155\/2022\/3053277","type":"journal-article","created":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T18:50:38Z","timestamp":1647456638000},"page":"1-5","source":"Crossref","is-referenced-by-count":5,"title":["Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1237-8671","authenticated-orcid":true,"given":"Zhenyun","family":"Dou","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Huai\u2019an Maternity and Child Health Hospital, Affiliated Hospital of Yangzhou University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3256-8410","authenticated-orcid":true,"given":"Zhou","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Hongze District People\u2019s Hospital, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3447-3709","authenticated-orcid":true,"given":"Qizheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Huai\u2019an Maternity and Child Health Hospital, Affiliated Hospital of Yangzhou University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8248-0671","authenticated-orcid":true,"given":"Jiangshu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Huai\u2019an Maternity and Child Health Hospital, Affiliated Hospital of Yangzhou University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2995-5682","authenticated-orcid":true,"given":"Chunlin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Huai\u2019an Maternity and Child Health Hospital, Affiliated Hospital of Yangzhou University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5493-9943","authenticated-orcid":true,"given":"Yequan","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Huai\u2019an Maternity and Child Health Hospital, Affiliated Hospital of Yangzhou University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3027-5027","authenticated-orcid":true,"given":"Tailiang","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Huai\u2019an Maternity and Child Health Hospital, Affiliated Hospital of Yangzhou University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6332-2101","authenticated-orcid":true,"given":"Haijun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Lianshui County People\u2019s Hospital, Affiliated Hospital of Kangda College, Nanjing Medical University, Huai\u2019an 223002, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"325","article-title":"LIU huayi and Chinese journal of integrated traditional and western medicine digestion liu J","volume":"027","author":"P. 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Yan","year":"2019","journal-title":"Observation on the effect of compound digestive enzyme capsule combined with mosapride on postprandial discomfort syndrome"},{"key":"20","first-page":"299","article-title":"Effect of different drugs on Tibetan patients with functional dyspepsia","volume":"051","author":"Huanhui","year":"2020","journal-title":"Gastric Volume Affected by Gastric Electromyography"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419857596"},{"key":"22","first-page":"2244","article-title":"Clinical laboratory medicine and clinical effects of liang J","volume":"016","year":"2019","journal-title":"Mosapride tablet combined with Shugan Jianpi Decoction on functional dyspepsia of Liver stagnation and spleen deficiency and its effect on gastrointestinal hormone secretion"}],"updated-by":[{"DOI":"10.1155\/2023\/9837474","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000},"record-id":"52308"},{"DOI":"10.1155\/2023\/9837474","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000}}],"container-title":["Journal of Healthcare Engineering"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jhe\/2022\/3053277.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jhe\/2022\/3053277.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jhe\/2022\/3053277.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T18:50:49Z","timestamp":1647456649000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jhe\/2022\/3053277\/"}},"subtitle":[],"editor":[{"given":"M. A","family":"Bhagyaveni","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,3,16]]},"references-count":22,"alternative-id":["3053277","3053277"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3053277","relation":{},"ISSN":["2040-2309","2040-2295"],"issn-type":[{"value":"2040-2309","type":"electronic"},{"value":"2040-2295","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3,16]]}}}