{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:46:05Z","timestamp":1769726765339,"version":"3.49.0"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":219,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. In order to explore the correlation between the retinol binding protein 4 (RBP4) and prognosis of patients with acute ischemic stroke (AIS), CT perfusion imaging can be used to scan the brain tissue of patients, which can identify abnormal perfusion areas and ischemic penumbra brain tissue, so as to provide a basis for doctors to formulate a reasonable clinical treatment plan. <jats:italic>Methods<\/jats:italic>. 200 patients with first\u2010episode acute ischemic stroke were selected from the Department of Neurology of our hospital, including 128 males and 72 females, aged between 32 and 85 years, with an average age of 45\u2009\u00b1\u20094.3 years. After admission, the patients were tested for xanthol binding protein 4 in time, the patient\u2019s demographic data and the basic clinical data were recorded, the degree of brain injury was evaluated, and the short\u2010term outcome was evaluated after treatment. <jats:italic>Results<\/jats:italic>. A total of 200 AIS patients with different degrees of brain injury were included in this study, including 128 males and 78 females, aged between 32 and 85 years, with an average age of 45\u2009\u00b1\u20094.3 years. Among them, 100 patients used CT perfusion imaging for brain scanning as the observation group, 100 patients used traditional imaging methods as the reference group, and 100 healthy people were included as the blank group. At the same time, the contents of total cholesterol, triacylglycerol, high\u2010density lipoprotein cholesterol, and low\u2010density lipoprotein cholesterol were measured by using an automatic biochemical analyzer. The patients were evaluated in the early stage of treatment and the effect of prognostic intervention was recorded. <jats:italic>Conclusion<\/jats:italic>. The application of CT perfusion imaging in the adjuvant treatment of AIS patients was helpful to identify the abnormal perfusion area and the brain tissue of ischemic penumbra, so as to provide a basis for doctors\u2019 follow\u2010up treatment. At the same time, AIS patients with high serum RBP4 level had mild stroke severity, good short\u2010term prognosis, and improved treatment effect, which improved patients\u2019 quality of life.<\/jats:p>","DOI":"10.1155\/2022\/3055712","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T18:35:19Z","timestamp":1659983719000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Correlation between Retinol Binding Protein 4 and CT Perfusion Imaging and Prognosis in Patients with Acute Ischemic Stroke Based on Cell Imaging Data Analysis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0580-2857","authenticated-orcid":false,"given":"Chao","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juxian","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongwei","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"e_1_2_10_1_2","first-page":"46","article-title":"Analysis of risk factors of intracerebral hemorrhage after thrombolysis in patients with acute ischemic stroke","volume":"28","author":"Shanshan L.","year":"2022","journal-title":"Contemporary medicine"},{"key":"e_1_2_10_2_2","first-page":"101","article-title":"Ma Zheng Relationship between serum retinol binding protein 4 and 8-Isoprostaglandin levels and disease severity and prognosis in patients with AIS","volume":"30","author":"Wang Q.","year":"2022","journal-title":"Journal of brain and neurological diseases"},{"key":"e_1_2_10_3_2","first-page":"875","article-title":"Correlation between serum retinol binding protein 4 level and short-term outcome in patients with acute ischemic stroke","volume":"18","author":"Zhang X.","year":"2019","journal-title":"China Health Engineering"},{"key":"e_1_2_10_4_2","first-page":"161","article-title":"Correlation between serum retinol binding protein 4 and stroke severity and short-term outcome in patients with acute ischemic stroke","author":"Huang X.","year":"2019","journal-title":"International Journal of cerebrovascular diseases"},{"key":"e_1_2_10_5_2","first-page":"179","article-title":"Lin Ximin Predictive value of ankle brachial index combined with serum retinol binding protein 4 and lipoprotein phospholipase A2 in diabetic patients with ischemic stroke","volume":"11","author":"Song W.","year":"2021","journal-title":"Chinese medical science"},{"key":"e_1_2_10_6_2","first-page":"3818","article-title":"Relationship between retinol binding protein 4 and cerebral infarction volume in patients with acute ischemic stroke and its predictive value for disease severity","volume":"35","author":"Hou D.","year":"2019","journal-title":"Journal of practical medicine"},{"key":"e_1_2_10_7_2","first-page":"139","article-title":"Multimodal deep learning model for diabetic retinopathy stages based on ultra wide fluorescein angiography","volume":"38","author":"Fan W.","year":"2022","journal-title":"The Chinese Journal of Fundus Diseases"},{"key":"e_1_2_10_8_2","first-page":"150","article-title":"Relationship between monocyte\/high density lipoprotein cholesterol ratio, cerebral collateral circulation and neurological deficit in patients with acute ischemic stroke","volume":"19","author":"Cheng W. P.","year":"2022","journal-title":"Clinical Journal of practical hospital"}],"container-title":["Contrast Media &amp; Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2022\/3055712.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2022\/3055712.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2022\/3055712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T06:58:57Z","timestamp":1721804337000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/3055712"}},"subtitle":[],"editor":[{"given":"Mohammad Farukh","family":"Hashmi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1155\/2022\/3055712"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3055712","archive":["Portico"],"relation":{},"ISSN":["1555-4309","1555-4317"],"issn-type":[{"value":"1555-4309","type":"print"},{"value":"1555-4317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2022-05-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3055712"}}