{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T01:42:54Z","timestamp":1776390174578,"version":"3.51.2"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T00:00:00Z","timestamp":1657152000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2022,7,7]]},"abstract":"<jats:p>Background. In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. Case Presentation. A 48-year-old patient presented with a large fungating mass near her right inferior vulva with a hardness of surrounding tissues. The mass was <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>4<\/a:mn>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mtext>cm<\/a:mtext>\n                        <a:mo>\u00d7<\/a:mo>\n                        <a:mn>3<\/a:mn>\n                        <a:mtext>\u2009<\/a:mtext>\n                        <a:mtext>cm<\/a:mtext>\n                     <\/a:math>\n                  <\/jats:inline-formula> in size and was excised in the operating room. The pathology was negative for malignancy; however, it showed lymphoplasmacytic proliferation with immunostaining positive for HSV virus. Conclusion. Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.<\/jats:p>","DOI":"10.1155\/2022\/3109331","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T20:50:07Z","timestamp":1657227007000},"page":"1-3","source":"Crossref","is-referenced-by-count":2,"title":["Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression"],"prefix":"10.1155","volume":"2022","author":[{"given":"Daniel","family":"York","sequence":"first","affiliation":[{"name":"Colquitt Regional Medical Center, Sterling Center Women\u2019s Health, Moultrie GA 31768, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1102-2080","authenticated-orcid":true,"given":"Pavan","family":"Patel","sequence":"additional","affiliation":[{"name":"Philadelphia College of Osteopathic Medicine, Moultrie, GA 31768, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smera","family":"Saikumar","sequence":"additional","affiliation":[{"name":"Philadelphia College of Osteopathic Medicine, Moultrie, GA 31768, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"4","key":"1","first-page":"204","article-title":"Drug-resistant herpes simplex virus in HIV infected patients","volume":"16","author":"M. S. Lolis","year":"2008","journal-title":"Acta dermatovenerologica Croatica: ADC"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30405-X"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/537939"},{"key":"4","article-title":"Herpes Simplex Type 2","volume-title":"StatPearls","author":"J. Mathew","year":"2022"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2008.0143"},{"issue":"2","key":"6","first-page":"205","article-title":"Disseminated herpes simplex infection in a HIV+ patient","volume":"144","author":"F. Dinotta","year":"2009","journal-title":"Giornale Italiano Di Dermatologia E Venereologia: Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia"},{"issue":"2","key":"7","first-page":"41","article-title":"Management of genital herpes in HIV-infected patients","volume":"8","author":"F. Y. Aoki","year":"2001","journal-title":"Herpes: The Journal of the IHMF"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1086\/505496"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2006"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006492.pub3"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2022\/3109331.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2022\/3109331.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2022\/3109331.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T20:50:14Z","timestamp":1657227014000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criog\/2022\/3109331\/"}},"subtitle":[],"editor":[{"given":"Seung-Yup","family":"Ku","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,7,7]]},"references-count":10,"alternative-id":["3109331","3109331"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3109331","relation":{},"ISSN":["2090-6692","2090-6684"],"issn-type":[{"value":"2090-6692","type":"electronic"},{"value":"2090-6684","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7,7]]}}}