{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T05:44:19Z","timestamp":1770356659224,"version":"3.49.0"},"reference-count":150,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"vor","delay-in-days":210,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BE2021650"],"award-info":[{"award-number":["BE2021650"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20200198"],"award-info":[{"award-number":["BK20200198"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82074473"],"award-info":[{"award-number":["82074473"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072498"],"award-info":[{"award-number":["82072498"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072425"],"award-info":[{"award-number":["82072425"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Ferroptosis is a new programmed cell death characterized by the accumulation of lipid peroxidation mediated by iron and inflammation. Since the transcentury realization of ferroptosis as an iron\u2010dependent modality of nonapoptotic cell death in 2012, there has been growing interest in the function of ferroptosis and its relationship to clinical diseases. Recent studies have shown that ferroptosis is associated with multiple diseases, including degenerative diseases, ischemia reperfusion injury, cardiovascular disease, and cancer. Cell death induced by ferroptosis has also been related to several skeletal diseases, such as inflammatory arthritis, osteoporosis, and osteoarthritis. Research on ferroptosis can clarify the pathogenesis of skeletal diseases and provide a novel therapeutic target for its treatment. In this review, we summarize current information about the molecular mechanism of ferroptosis and describe its emerging role and therapeutic potential in skeletal diseases.<\/jats:p>","DOI":"10.1155\/2022\/3112388","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T19:35:06Z","timestamp":1659209706000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Emerging Potential Therapeutic Targets of Ferroptosis in Skeletal Diseases"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8681-5096","authenticated-orcid":false,"given":"Xin","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8334-2476","authenticated-orcid":false,"given":"Tianhao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0493-4391","authenticated-orcid":false,"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6551-9469","authenticated-orcid":false,"given":"Xiaolong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1182-290X","authenticated-orcid":false,"given":"Yating","family":"Mu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9168-2929","authenticated-orcid":false,"given":"Yaozeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3485-5563","authenticated-orcid":false,"given":"Jiaxiang","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4375-2803","authenticated-orcid":false,"given":"Dechun","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,30]]},"reference":[{"key":"e_1_2_15_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.042"},{"key":"e_1_2_15_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1416"},{"key":"e_1_2_15_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.09.021"},{"key":"e_1_2_15_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2008.02.010"},{"key":"e_1_2_15_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05859"},{"key":"e_1_2_15_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2015.158"},{"key":"e_1_2_15_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.12.010"},{"key":"e_1_2_15_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/82_2016_508"},{"key":"e_1_2_15_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2017.02.005"},{"key":"e_1_2_15_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.02.015"},{"key":"e_1_2_15_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.06.011"},{"key":"e_1_2_15_12_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8010614"},{"key":"e_1_2_15_13_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2018"},{"key":"e_1_2_15_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03559-1"},{"key":"e_1_2_15_15_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.822083"},{"key":"e_1_2_15_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-022-01530-y"},{"key":"e_1_2_15_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbin.11121"},{"key":"e_1_2_15_18_2","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.245480"},{"key":"e_1_2_15_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700900210"},{"key":"e_1_2_15_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1910(65)90099-5"},{"key":"e_1_2_15_21_2","doi-asserted-by":"publisher","DOI":"10.3109\/10715769109093424"},{"key":"e_1_2_15_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)40252-4"},{"key":"e_1_2_15_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(82)90150-3"},{"key":"e_1_2_15_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-711X(94)90097-3"},{"key":"e_1_2_15_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00050-3"},{"key":"e_1_2_15_26_2","doi-asserted-by":"publisher","DOI":"10.2174\/1568026013394741"},{"key":"e_1_2_15_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)90334-4"},{"key":"e_1_2_15_28_2","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2000.2.4-665"},{"key":"e_1_2_15_29_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.122.3168.501"},{"key":"e_1_2_15_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2003.08.009"},{"key":"e_1_2_15_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja411006a"},{"key":"e_1_2_15_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2014.11.014"},{"key":"e_1_2_15_33_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.11687"},{"key":"e_1_2_15_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.10.426"},{"key":"e_1_2_15_35_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12040827"},{"key":"e_1_2_15_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.11.3061"},{"key":"e_1_2_15_37_2","doi-asserted-by":"publisher","DOI":"10.1177\/153537020623100403"},{"key":"e_1_2_15_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13105-013-0266-3"},{"key":"e_1_2_15_39_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00077"},{"key":"e_1_2_15_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1692"},{"key":"e_1_2_15_41_2","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.100234"},{"key":"e_1_2_15_42_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-110-6-430"},{"key":"e_1_2_15_43_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3064"},{"key":"e_1_2_15_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/cas.14181"},{"key":"e_1_2_15_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(97)01289-2"},{"key":"e_1_2_15_46_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9030205"},{"key":"e_1_2_15_47_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105941108"},{"key":"e_1_2_15_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28159"},{"key":"e_1_2_15_49_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-021-01053-7"},{"key":"e_1_2_15_50_2","first-page":"6417","article-title":"Sorafenib induces ferroptosis in human cancer cell lines originating from different solid tumors","volume":"34","author":"Lachaier E.","year":"2014","journal-title":"Anticancer Research"},{"key":"e_1_2_15_51_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28251"},{"key":"e_1_2_15_52_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.02523"},{"key":"e_1_2_15_53_2","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13142"},{"key":"e_1_2_15_54_2","doi-asserted-by":"publisher","DOI":"10.18632\/aging.103378"},{"key":"e_1_2_15_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.5882"},{"key":"e_1_2_15_56_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1783485"},{"key":"e_1_2_15_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2019.10.006"},{"key":"e_1_2_15_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2019.11.004"},{"key":"e_1_2_15_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2019.10.007"},{"key":"e_1_2_15_60_2","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202013792"},{"key":"e_1_2_15_61_2","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2015.1068479"},{"key":"e_1_2_15_62_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature14344"},{"key":"e_1_2_15_63_2","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2017.7115"},{"key":"e_1_2_15_64_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M001280200"},{"key":"e_1_2_15_65_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-01058-1"},{"key":"e_1_2_15_66_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13008"},{"key":"e_1_2_15_67_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1607152113"},{"key":"e_1_2_15_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.12.077"},{"key":"e_1_2_15_69_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10565-021-09624-x"},{"key":"e_1_2_15_70_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers10060154"},{"key":"e_1_2_15_71_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7507857"},{"key":"e_1_2_15_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.07.055"},{"key":"e_1_2_15_73_2","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1148"},{"key":"e_1_2_15_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2015.11.012"},{"key":"e_1_2_15_75_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.5162"},{"key":"e_1_2_15_76_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2015.32"},{"key":"e_1_2_15_77_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/230182"},{"key":"e_1_2_15_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2015.10.014"},{"key":"e_1_2_15_79_2","doi-asserted-by":"publisher","DOI":"10.3390\/biology10030184"},{"key":"e_1_2_15_80_2","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16059"},{"key":"e_1_2_15_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.047"},{"key":"e_1_2_15_82_2","first-page":"14","article-title":"Risk factors for osteoporosis and associated fractures","volume":"104","author":"Kelsey J. L.","year":"1989","journal-title":"Public Health Reports"},{"key":"e_1_2_15_83_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.46.1.249"},{"key":"e_1_2_15_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00420-9"},{"key":"e_1_2_15_85_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2014.35"},{"key":"e_1_2_15_86_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.2611"},{"key":"e_1_2_15_87_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/1295382"},{"key":"e_1_2_15_88_2","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2022.12656"},{"key":"e_1_2_15_89_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/9067610"},{"key":"e_1_2_15_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2021.04.027"},{"key":"e_1_2_15_91_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12700"},{"key":"e_1_2_15_92_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/2634431"},{"key":"e_1_2_15_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medine.2016.11.007"},{"key":"e_1_2_15_94_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201903171R"},{"key":"e_1_2_15_95_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-011-0882-3"},{"key":"e_1_2_15_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105069"},{"key":"e_1_2_15_97_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8100195"},{"key":"e_1_2_15_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2019.110669"},{"key":"e_1_2_15_99_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003555"},{"key":"e_1_2_15_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2021.102185"},{"key":"e_1_2_15_101_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11010150"},{"key":"e_1_2_15_102_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-019-03039-1"},{"key":"e_1_2_15_103_2","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2011.96"},{"key":"e_1_2_15_104_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2018.10.023"},{"key":"e_1_2_15_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2020.104570"},{"key":"e_1_2_15_106_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq276"},{"key":"e_1_2_15_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2021.02.137"},{"key":"e_1_2_15_108_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.111202"},{"key":"e_1_2_15_109_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-020-0376-8"},{"key":"e_1_2_15_110_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5021983"},{"key":"e_1_2_15_111_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5021983"},{"key":"e_1_2_15_112_2","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-15-0380"},{"key":"e_1_2_15_113_2","doi-asserted-by":"publisher","DOI":"10.1177\/153537020422900817"},{"key":"e_1_2_15_114_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60802-3"},{"key":"e_1_2_15_115_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32279-7"},{"key":"e_1_2_15_116_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2019.10.007"},{"key":"e_1_2_15_117_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms16036093"},{"key":"e_1_2_15_118_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17010130"},{"key":"e_1_2_15_119_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2020.09.006"},{"key":"e_1_2_15_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2019.101107"},{"key":"e_1_2_15_121_2","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13134"},{"key":"e_1_2_15_122_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2022.103847"},{"key":"e_1_2_15_123_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2015.0429"},{"key":"e_1_2_15_124_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30173-8"},{"key":"e_1_2_15_125_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1199214"},{"key":"e_1_2_15_126_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-011-2133-2"},{"key":"e_1_2_15_127_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1608345"},{"key":"e_1_2_15_128_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.123919"},{"key":"e_1_2_15_129_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-00993-3"},{"key":"e_1_2_15_130_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2020.04.001"},{"key":"e_1_2_15_131_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-27948-4"},{"key":"e_1_2_15_132_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119730"},{"key":"e_1_2_15_133_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5080843"},{"key":"e_1_2_15_134_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1707-0"},{"key":"e_1_2_15_135_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1705-2"},{"key":"e_1_2_15_136_2","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.9504"},{"key":"e_1_2_15_137_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-019-1307-6"},{"key":"e_1_2_15_138_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00253-0"},{"key":"e_1_2_15_139_2","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2018.9054"},{"key":"e_1_2_15_140_2","doi-asserted-by":"publisher","DOI":"10.2147\/dddt.s175763"},{"key":"e_1_2_15_141_2","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1810918"},{"key":"e_1_2_15_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2020.02.009"},{"key":"e_1_2_15_143_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-022-00198-w"},{"key":"e_1_2_15_144_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.03.032"},{"key":"e_1_2_15_145_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2017.11.015"},{"key":"e_1_2_15_146_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00214"},{"key":"e_1_2_15_147_2","doi-asserted-by":"publisher","DOI":"10.1159\/000490807"},{"key":"e_1_2_15_148_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01120"},{"key":"e_1_2_15_149_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20210518"},{"key":"e_1_2_15_150_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.779585"}],"container-title":["Oxidative Medicine and Cellular Longevity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2022\/3112388.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2022\/3112388.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2022\/3112388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:32:14Z","timestamp":1748910734000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/3112388"}},"subtitle":[],"editor":[{"given":"Lianxiang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":150,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1155\/2022\/3112388"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3112388","archive":["Portico"],"relation":{},"ISSN":["1942-0900","1942-0994"],"issn-type":[{"value":"1942-0900","type":"print"},{"value":"1942-0994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2022-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3112388"}}