{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T14:24:17Z","timestamp":1772202257740,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T00:00:00Z","timestamp":1642982400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Foundation of Beijing","award":["7204264"],"award-info":[{"award-number":["7204264"]}]},{"name":"Natural Science Foundation of Beijing","award":["2019YFC0120604"],"award-info":[{"award-number":["2019YFC0120604"]}]},{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["7204264"],"award-info":[{"award-number":["7204264"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2019YFC0120604"],"award-info":[{"award-number":["2019YFC0120604"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2022,1,24]]},"abstract":"<jats:p>Background. The surgical management of cervical degenerative disc degeneration (CDDD) has not reached a consensus. Artificial cervical disc replacement (ACDR) has been shown to be efficient in reducing symptoms after CDDD, although the topic remains highly controversial in this field. This study aimed to evaluate the effectiveness of ACDR on the treatment of CDDD on the aspect of radiographic reconstruction and clinical improvement compared with anterior cervical discectomy and fusion (ACDF). Methods. This was a retrospective comparative study with 47 patients who underwent single-level ACDR and 46 patients who underwent single-level ACDF. The radiographic reconstruction was assessed by the cervical sagittal alignment parameters, consisting of two aspects, distance and angle, such as cervical sagittal vertical axis (cSVA), cervical lordosis (CL), T1 slope (T1s), and intervertebral space height (ISH). The clinical improvement was assessed by patient-related outcomes (PROs), consisting of two aspects, relief of axial neck pain and recovery of cervical dysfunction, measured through the Visual Analogue Scale (VAS), Neck Disability Index (NDI), and Japanese Orthopedic Association (JOA). Results. Significant variations were achieved on aspects of radiographic reconstruction and clinical improvement after ACDR (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>), which were similar to that of the ACDF group (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). A significantly larger postoperative range of motion (ROM) was found in patients less than 45 years of age in the ACDR group (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). In addition, a significantly better postoperative JOA was found in patients with a preoperative ISH less than 4\u2009mm in the ACDF group than that in the ACDR group (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). Other than that mentioned above, no significant variations in radiographic and clinical outcomes were found between the two groups (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&gt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). Conclusions. Overall, this study showed that a similar capability in terms of radiographic reconstruction and clinical improvement was found between the two methods. Specific concerns should be analyzed while choosing between an ACDR and an ACDF. It should be pointed out that, based on our experience, if the patient is younger, ACDR is recommended; for patients with preoperative ISH less than 4\u2009mm, ACDF is more recommended.<\/jats:p>","DOI":"10.1155\/2022\/3353810","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T18:05:09Z","timestamp":1643047509000},"page":"1-8","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of Radiographic Reconstruction and Clinical Improvement between Artificial Cervical Disc Replacement and Anterior Cervical Discectomy and Fusion"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1458-5743","authenticated-orcid":true,"given":"Yuxiang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6924-8969","authenticated-orcid":true,"given":"Yue","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7206-325X","authenticated-orcid":true,"given":"Yong","family":"Hai","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9984-7663","authenticated-orcid":true,"given":"Peng","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2128-4594","authenticated-orcid":true,"given":"Yuzeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2779-7593","authenticated-orcid":true,"given":"Jincai","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingjun","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong Ti Nan Road, Chaoyang, Beijing 100020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-019-04129-3"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199309000-00005"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-018-04281-y"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyaa459"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2021.106493"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-019-06157-0"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3171\/2013.4.spine12838"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.5435\/jaaos-21-01-3"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199904000-00009"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3171\/spi-07\/09\/336"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/brs.0000000000000636"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/brs.0000000000001044"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.08.010"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.09.069"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-020-02157-9"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.3171\/2018.9.spine18659"},{"issue":"9","key":"17","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1097\/BRS.0b013e3182797592","article-title":"Five-year reoperation rates, cervical total disc replacement versus fusion, results of a prospective randomized clinical trial","volume":"38","author":"R. 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