{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T14:50:15Z","timestamp":1774450215588,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T00:00:00Z","timestamp":1658534400000},"content-version":"vor","delay-in-days":203,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic> This study aimed to evaluate the safety and efficacy of the fixation of transforaminal sacral fractures using TiRobot\u2010assisted transiliac\u2010transsacral (TITS) screws under multimodal neuroelectrophysiological monitoring (MNM). <jats:italic>Methods<\/jats:italic>. From January 2019 to May 2021, 22 patients (17 male and 5 female patients) with transforaminal sacral fractures who were treated with closed reduction and placement of TiRobot\u2010assisted TITS screws under MNM were retrospectively evaluated. The average age of the patients was 43.32\u2009\u00b1\u200911.40 years (range: 19\u201363). The patients received MNM, including somatosensory\u2010evoked potentials (SEPs), motor\u2010evoked potentials (MEPs), and electromyographic monitoring (EMG), prior to surgery, during closed reduction and the placement of the guidewire and TITS screw, and at the end of surgery. The operation was adjusted according to the MNM results. <jats:italic>Results<\/jats:italic>. Overall, 22 TITS screws were inserted in 22 patients, including 5 TITS screws in the S1 body and 17 TITS screws in the S2 body. The average time needed for screw placement was 27.95\u2009\u00b1\u20096.84\u2009mins, and the average frequency of X\u2010ray fluoroscopy exposures was 31.00\u2009\u00b1\u20095.56 for each patient. Anterior ring fixation was performed in 4 patients using an external fixator, in 5 patients using cannulated screws, and in 13 patients using reconstruction plates. The mean follow\u2010up time was 14.46\u2009\u00b1\u20092.46 months (12\u201320 months). Tornetta and Matta radiographic outcomes were excellent in 10 patients, good in 9 patients, fair in 2 patients, and poor in 1 patient. The proportion of excellent and good ratings was 86.36%. At the final follow\u2010up, the average Majeed score was 82.18\u2009\u00b1\u200914.52, with clinical outcomes that were excellent in 9 patients, good in 9 patients, fair in 1 patient, and poor in 3 patients. The proportion of excellent and good ratings was 82.82%. Preoperatively, the amplitude of the SEP on the injured side was lower than that on the contralateral side before reduction in 9 patients (&gt;50%). In this study, no screw was mistakenly inserted into the sacral canal, and no surgical site infection occurred. <jats:italic>Conclusion<\/jats:italic>. MNM combined with TiRobot assistance can safely implant TITS screws and can effectively identify the neurological function of patients under anesthesia and reduce iatrogenic nerve injury.<\/jats:p>","DOI":"10.1155\/2022\/3383665","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T18:35:09Z","timestamp":1658601309000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Multimodal Neuroelectrophysiological Monitoring Combined with Robot\u2010Assisted Placement of a Transiliac\u2013Transsacral Screw for the Treatment of Transforaminal Sacral Fractures"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8075-5873","authenticated-orcid":false,"given":"Pengfei","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaguang","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinan","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4390-1469","authenticated-orcid":false,"given":"Chen","family":"Fei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahui","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongli","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5210-6331","authenticated-orcid":false,"given":"Kun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6816-3071","authenticated-orcid":false,"given":"Yan","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,23]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2021.03.013"},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00113-012-2335-4"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001130050585"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3181af69be"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0000000000000418"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.5249\/jivr.v5i2.138"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.55095\/achot2013\/033"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-007-0468-9"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-199506000-00005"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0000000000001796"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-019-1472-7"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e3181e47fad"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-199711000-00007"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2013.03.023"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2367-z"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2020.11.044"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066620962453"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11420-013-9347-7"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200109000-00012"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/1086508X.2006.11079587"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-007-0417-8"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.71B2.2925751"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199608000-00022"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.91B9.22093"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2014.10.058"},{"key":"e_1_2_11_26_2","first-page":"896","article-title":"Biomechanical comparisons of two sacroiliac screws with different lengths in the treatment of central sacral fractures in a finite element model","volume":"33","author":"Zhao Y.","year":"2017","journal-title":"Chinese Journal of Traumatology"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-014-3313-z"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005860050081"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-199212000-00005"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-019-03207-6"},{"key":"e_1_2_11_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/os.12461"},{"key":"e_1_2_11_32_2","first-page":"191","article-title":"Influences of lateral, front-rear and rotational displacements on injury to sacral nerves in fractures of sacral zone II","volume":"17","author":"Guang Y.","year":"2015","journal-title":"Chinese Journal of Orthopaedic Trauma"},{"key":"e_1_2_11_33_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.72.6.0889"},{"key":"e_1_2_11_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200302000-00002"},{"key":"e_1_2_11_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-018-5861-0"},{"key":"e_1_2_11_36_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.103B3.BJJ-2020-1278.R1"},{"key":"e_1_2_11_37_2","doi-asserted-by":"publisher","DOI":"10.1159\/000501256"},{"key":"e_1_2_11_38_2","doi-asserted-by":"publisher","DOI":"10.5137\/1019-5149.JTN.16414-15.1"},{"key":"e_1_2_11_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-4231(07)08055-0"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2022\/3383665.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2022\/3383665.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2022\/3383665","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:35:06Z","timestamp":1735691706000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2022\/3383665"}},"subtitle":[],"editor":[{"given":"Panagiotis","family":"Korovessis","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1155\/2022\/3383665"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3383665","archive":["Portico"],"relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2022-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"3383665"}}