{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T23:52:39Z","timestamp":1781221959933,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T00:00:00Z","timestamp":1655683200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,6,20]]},"abstract":"<jats:p>This study was to investigate the cardiac function characteristics under two-dimensional ultrasound and triplane tissue Doppler imaging (TDI) of patients with severe preeclampsia (SPE). 28 SPE patients with singleton pregnancy from January 2018 to December 2020 were included in the SPE group. 25 healthy nonpregnant women of reproductive age were taken as the control group (Ctrl group), and 26 normal pregnant women with singleton pregnancy were selected as the normal group (Norm group); all the research objects underwent ultrasonography. The morphological and functional indexes of left and right ventricles were compared among the cases in different groups. The results showed that the left ventricular end-diastolic period diameter (LVEDd), left ventricular relative wall thickness (LV-RWT), left ventricular mass index (LVMi), left anterior descending (LAd), left ventricular <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>E<\/a:mi>\n                        <a:mo>\/<\/a:mo>\n                        <a:mi>e<\/a:mi>\n                     <\/a:math>\n                  <\/jats:inline-formula> and <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>e<\/c:mi>\n                        <c:mo>\/<\/c:mo>\n                        <c:mi>a<\/c:mi>\n                     <\/c:math>\n                  <\/jats:inline-formula> values, right ventricular diameter (RV-D), right ventricular anterior wall thickness (RVAW), <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>a<\/e:mi>\n                     <\/e:math>\n                  <\/jats:inline-formula> value, right atrial septum (RA-S), pulmonary artery systolic pressure (PASP), left ventricular end-systolic period diameter (LVEds), interventricular septal thickness (IVSd), posterior wall thickness (PWd), end-diastolic period volume (EVD), end-systolic period volume (ESV), relative wall thickness (RWT), sphericity index (SpI), left atrium volume index (LAVi), and <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>E<\/g:mi>\n                        <g:mo>\/<\/g:mo>\n                        <g:mi>e<\/g:mi>\n                     <\/g:math>\n                  <\/jats:inline-formula> value of patients in the SPE group were higher than those in the Ctrl group and the Norm group (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). The mitral annular plane systolic excursion (MAPSE), <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>s<\/k:mi>\n                     <\/k:math>\n                  <\/jats:inline-formula> value, tricuspid annual plane systolic excursion (TAPSE), ratio of early diastolic blood flow velocity to late diastolic blood flow velocity (<jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mi>E<\/m:mi>\n                        <m:mo>\/<\/m:mo>\n                        <m:mi>A<\/m:mi>\n                     <\/m:math>\n                  <\/jats:inline-formula>), ratio of peak early diastolic velocity to peak late diastolic velocity (<jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mi>e<\/o:mi>\n                        <o:mo>\/<\/o:mo>\n                        <o:mi>a<\/o:mi>\n                     <\/o:math>\n                  <\/jats:inline-formula>), peak early diastolic velocity (<jats:inline-formula>\n                     <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mi>e<\/q:mi>\n                     <\/q:math>\n                  <\/jats:inline-formula>), and ejection fraction (EF) of the SPE group were lower than those of the Ctrl group and the Norm group (<jats:inline-formula>\n                     <s:math xmlns:s=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                        <s:mi>P<\/s:mi>\n                        <s:mo>&lt;<\/s:mo>\n                        <s:mn>0.05<\/s:mn>\n                     <\/s:math>\n                  <\/jats:inline-formula>). The ratio of mitral valve early diastolic blood flow velocity to peak early diastolic velocity (<jats:inline-formula>\n                     <u:math xmlns:u=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                        <u:mi>E<\/u:mi>\n                        <u:mo>\/<\/u:mo>\n                        <u:mi>e<\/u:mi>\n                     <\/u:math>\n                  <\/jats:inline-formula>) of the Norm group was higher than that of the Ctrl group (<jats:inline-formula>\n                     <w:math xmlns:w=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\">\n                        <w:mi>P<\/w:mi>\n                        <w:mo>&lt;<\/w:mo>\n                        <w:mn>0.05<\/w:mn>\n                     <\/w:math>\n                  <\/jats:inline-formula>). In two-dimensional ultrasound of the SPE group, the maximum difference in time from the start to the peak of systole (Ts) of the right ventricle between the basal and middle segments of the lateral wall and that of interventricular septum (RV-Ts-max) was <jats:inline-formula>\n                     <y:math xmlns:y=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\">\n                        <y:mn>31.56<\/y:mn>\n                        <y:mo>\u00b1<\/y:mo>\n                        <y:mn>0.39<\/y:mn>\n                        <y:mi>%<\/y:mi>\n                     <\/y:math>\n                  <\/jats:inline-formula>. The maximum difference in time to peak of early diastole (Te) under the same condition (RV-Te-max) was <jats:inline-formula>\n                     <ab:math xmlns:ab=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\">\n                        <ab:mn>47.16<\/ab:mn>\n                        <ab:mo>\u00b1<\/ab:mo>\n                        <ab:mn>0.19<\/ab:mn>\n                        <ab:mi>%<\/ab:mi>\n                     <\/ab:math>\n                  <\/jats:inline-formula>. Left ventricular LV-Ts-max and LV-Te-max were <jats:inline-formula>\n                     <cb:math xmlns:cb=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M15\">\n                        <cb:mn>9.83<\/cb:mn>\n                        <cb:mo>\u00b1<\/cb:mo>\n                        <cb:mn>0.80<\/cb:mn>\n                        <cb:mi>%<\/cb:mi>\n                     <\/cb:math>\n                  <\/jats:inline-formula> and <jats:inline-formula>\n                     <eb:math xmlns:eb=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M16\">\n                        <eb:mn>8.37<\/eb:mn>\n                        <eb:mo>\u00b1<\/eb:mo>\n                        <eb:mn>0.68<\/eb:mn>\n                        <eb:mi>%<\/eb:mi>\n                     <\/eb:math>\n                  <\/jats:inline-formula>, respectively, in triplane TDI, which were considerably higher than those in the Ctrl and Norm groups (<jats:inline-formula>\n                     <gb:math xmlns:gb=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M17\">\n                        <gb:mi>P<\/gb:mi>\n                        <gb:mo>&lt;<\/gb:mo>\n                        <gb:mn>0.05<\/gb:mn>\n                     <\/gb:math>\n                  <\/jats:inline-formula>). It suggested that two-dimensional ultrasound and triplane TDI could reflect the ventricular morphology as well as diastolic and systolic function injury in patients, which offered a reference basis for the diagnosis of SPE.<\/jats:p>","DOI":"10.1155\/2022\/3384713","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T15:10:51Z","timestamp":1655737851000},"page":"1-10","source":"Crossref","is-referenced-by-count":2,"title":["Two-Dimensional Ultrasound and Triplane Tissue Doppler Ultrasound of Patients with Severe Preeclampsia"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1683-6086","authenticated-orcid":true,"given":"Huili","family":"Tong","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Weinan Maternal and Child Health Care Hospital, Weinan, 714000 Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8123-1262","authenticated-orcid":true,"given":"Yafeng","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Weinan Maternal and Child Health Care Hospital, Weinan, 714000 Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19002"},{"key":"2","first-page":"S53","article-title":"Alpha-1antitrypsin in pre-eclampsia; from a clinical perspective","volume":"71","author":"W. Nori","year":"2021","journal-title":"The Journal of the Pakistan Medical Association"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12802"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175914"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2019.11.002"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.104692"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.9745\/GHSP-D-19-00124"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_820_21"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1075034"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1692454"},{"issue":"4","key":"11","first-page":"3427","article-title":"Predictive value of vitamin A and E levels in pre-eclampsia and postpartum kidney injury","volume":"13","author":"N. 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