{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T10:24:57Z","timestamp":1781259897469,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Cangzhou Science and Technology Support Project","award":["162302172"],"award-info":[{"award-number":["162302172"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,6,30]]},"abstract":"<jats:p>Tumour necrosis factor (TNF) levels are higher in patients who have experienced an acute ischemic stroke. Greater levels of TNF may not be linked to an increased risk of recurrent coronary events in the stable phase after myocardial ischemia (MI). Coronary atheroma is connected to endothelial and smooth muscle cells, as well as macrophages that emit the multifunctional cytokine tumour necrosis factor (TNF). Transplanted tumours become more vulnerable when TNF-\u03b1 was first recognized to have a function in hemorrhagic necrosis. TNF-\u03b1 has been demonstrated to induce heart failure, pulmonary edoema, and cardiomyopathy in people with advanced heart failure when it is elevated in the bloodstream. It has been postulated that prolonged overexpression of TNF-\u03b1 after ischemia may contribute to poor cardiac outcomes by increasing TNF-\u03b1 when the myocardium undergoes both temporary ischemia and reperfusion. A rise in TNF levels has been seen after a myocardial infarction, but it is unclear if these higher levels, found months after the initial event, are associated with an increased risk of subsequent heart attacks. We looked at TNF levels in the blood of 270 patients with coronary heart disease in the Chinese Hypertension League\u2019s Cholesterol and Recurrent Events (CARE) experiment to see if this notion held true. Recurrent coronary syndrome and coronary mortality were monitored prospectively in the participants. The min max imbalance normalization can be used to assess a patient\u2019s baseline characteristics, including hormone and cholesterol test results. Type 2 stimulant connection to aggregate the TNF-signaling qualities and fuzzy techniques was applied. There may now be enough preliminary evidence from the crucial bundle neural network analysis to identify the risk of coronary heart disease associated with TNF pregeneration studies. The tests were assessed using a variety of methods and performance metrics in a Matlab environment.<\/jats:p>","DOI":"10.1155\/2022\/3439768","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T23:05:06Z","timestamp":1656630306000},"page":"1-13","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Features of Acute Coronary Syndrome in Patients with Coronary Heart Disease and Its Correlation with Tumour Necrosis Factor in Cardiology"],"prefix":"10.1155","volume":"2022","author":[{"given":"Run","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Cangzhou Central Hospital, Cangzhou, 061000 Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Cangzhou Central Hospital, Cangzhou, 061000 Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Cangzhou Central Hospital, Cangzhou, 061000 Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfang","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Cangzhou Central Hospital, Cangzhou, 061000 Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0146-087X","authenticated-orcid":true,"given":"Jun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Cangzhou Central Hospital, Cangzhou, 061000 Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0026-0495(98)90203-7"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.9685"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23593"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.12669\/pjms.37.3.3897"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.682959"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57060575"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8872686"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1080\/15287394.2021.1896404"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-020-01356-4"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-86207-0"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/3314457"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14951"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14964"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.119.009829"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2020.03.025"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/3602608"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/1584052"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8048691"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1631263"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/3041565"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8816805"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/3439768.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/3439768.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/3439768.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T23:05:09Z","timestamp":1656630309000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmm\/2022\/3439768\/"}},"subtitle":[],"editor":[{"given":"Naeem","family":"Jan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,6,30]]},"references-count":21,"alternative-id":["3439768","3439768"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3439768","relation":{},"ISSN":["1748-6718","1748-670X"],"issn-type":[{"value":"1748-6718","type":"electronic"},{"value":"1748-670X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,30]]}}}