{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:53:13Z","timestamp":1767167593337,"version":"build-2238731810"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T00:00:00Z","timestamp":1652227200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,5,11]]},"abstract":"\n Objective. To explore the clinical application of echocardiography in assessing left ventricular diastolic function in patients with acute pulmonary embolism (APE). Methods. About 90 patients with APE treated in our hospital from March 2016 to March 2019 were enrolled as the study group. The enrolled patients were assigned into three groups in accordance with the risk stratification of APE, with 30 patients in each group, including high-risk group, medium-risk group, and low-risk group. Approximately 90 healthy persons who underwent physical examination in the same period were enrolled as the control group. The two groups were used to analyze the clinical value of echocardiography in evaluating left ventricular diastolic function in patients with APE and to explore the correlation between left ventricular diastolic function and different risk stratification of APE. Results. First of all, we compared the side values of echocardiography. Compared to the control group, right ventricular end-diastolic diameter\/left ventricular end-diastolic diameter (RVED\/LVED) and pulmonary artery systolic pressure (PASP) in the study group were higher, while left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), left ventricular volume per stroke (LVSV), and left ventricular ejection fraction (LVEF) in the study group were lower (\n \n \n P<\/a:mi>\n <<\/a:mo>\n 0.05<\/a:mn>\n <\/a:math>\n <\/jats:inline-formula>\n ). Secondly, we compared the echocardiographic side values of patients with different APE risk stratifications: (1) RVED\/LVED, PASP:\n \n \n low<\/c:mtext>\n \u2010<\/c:mo>\n risk<\/c:mtext>\n \u2009<\/c:mtext>\n group<\/c:mtext>\n <<\/c:mo>\n medium<\/c:mtext>\n \u2010<\/c:mo>\n risk<\/c:mtext>\n \u2009<\/c:mtext>\n group<\/c:mtext>\n <<\/c:mo>\n high<\/c:mtext>\n \u2010<\/c:mo>\n risk<\/c:mtext>\n \u2009<\/c:mtext>\n group<\/c:mtext>\n <\/c:math>\n <\/jats:inline-formula>\n ; (2) LVEDV, LVESV, LVSV, LVEF:\n \n \n low<\/e:mtext>\n \u2010<\/e:mo>\n risk<\/e:mtext>\n \u2009<\/e:mtext>\n group<\/e:mtext>\n ><\/e:mo>\n medium<\/e:mtext>\n \u2010<\/e:mo>\n risk<\/e:mtext>\n \u2009<\/e:mtext>\n group<\/e:mtext>\n ><\/e:mo>\n high<\/e:mtext>\n \u2010<\/e:mo>\n risk<\/e:mtext>\n \u2009<\/e:mtext>\n group<\/e:mtext>\n <\/e:math>\n <\/jats:inline-formula>\n (\n \n \n P<\/g:mi>\n <<\/g:mo>\n 0.05<\/g:mn>\n <\/g:math>\n <\/jats:inline-formula>\n ). The routine echocardiographic findings of APE patients: M-type left ventricular wave group of pulmonary embolism (PE) indicated right ventricular enlargement and interventricular septum shifted to the left ventricle; short-axis section of PE artery indicated thrombosis at the opening of the right pulmonary artery (indicated by arrow); long-axis section of the left ventricle of PE indicated right ventricular enlargement (RV 3.5\u2009cm, LV 3.9\u2009cm); four-chamber view of PE indicated enlargement of the right atrium and the right ventricle, and interventricular septum shifted like left ventricle. In terms of mitral annulus displacement, early diastolic ESD and ELD in the study group were lower compared to those in the normal control group, while late diastolic ASD and ALD in the study group were higher compared to those in the normal control group (\n \n \n P<\/i:mi>\n <<\/i:mo>\n 0.05<\/i:mn>\n <\/i:math>\n <\/jats:inline-formula>\n ). The results of Pearson correlation analysis indicated that there was a positive correlation between RVED\/LVED, PASP, and APE risk stratification, while APE risk stratification was negatively correlated with LVEDV, LVESV, LVSV, and LVEF (\n \n \n P<\/k:mi>\n <<\/k:mo>\n 0.05<\/k:mn>\n <\/k:math>\n <\/jats:inline-formula>\n ). Conclusion. Echocardiography attaches importance to the evaluation of left ventricular diastolic function in APE. The side value of echocardiography can sensitively reflect the changes of left ventricular diastolic function in APE. The predictive value in the diagnosis of APE is better than other traditional parameters of left ventricular diastolic function, especially in patients with different APE risk stratifications. There is a remarkable correlation between the changes of left ventricular diastolic function and different APE risk stratifications. Echocardiographic measurement can be employed to assess left ventricular diastolic function in APE, which can be developed in clinical treatment and prognosis evaluation to provide a new evaluation method.\n <\/jats:p>","DOI":"10.1155\/2022\/3483390","type":"journal-article","created":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T19:06:46Z","timestamp":1652296006000},"page":"1-9","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Application of Echocardiography in Evaluating Left Ventricular Diastolic Function in Patients with Acute Pulmonary Embolism"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1218-5121","authenticated-orcid":true,"given":"Shiyang","family":"Qin","sequence":"first","affiliation":[{"name":"Department of Ultrasound, Affiliated Hospital of Chengde Medical College, Chengde Hebei 067000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Physical Examination, Affiliated Hospital of Chengde Medical College, Chengde Hebei 067000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"55","key":"1","first-page":"192","article-title":"Correlation between CT-derived cardiac chamber volume, myocardial injury and mortality in APE","volume":"205","author":"G. Yoav","year":"2021","journal-title":"Thrombosis Research"},{"issue":"10","key":"2","first-page":"140","article-title":"Detection of right ventricular dysfunction in APE by computed tomography or echocardiography: a systematic review and meta-analysis","volume":"19","author":"L. J. Chornenki Nicholas","year":"2021","journal-title":"Journal of thrombosis and haemostasis: JTH"},{"issue":"5","key":"3","first-page":"165","article-title":"An original risk score to predict early major bleeding in APE: the Syncope, Anemia, Renal Dysfunction (PE-SARD) bleeding score","volume":"160","author":"C. Romain","year":"2021","journal-title":"Chest"},{"issue":"33","key":"4","first-page":"193","article-title":"Right ventricle dysfunction in patients with APE supposedly at low risk for death: when evidence-based medicine rescues clinical practice","volume":"42","author":"B. Laurent","year":"2021","journal-title":"European Heart Journal"},{"issue":"7","key":"5","first-page":"186","article-title":"Temporal analysis of tachycardia during catheter directed thrombolysis for APE","volume":"55","author":"G. Assaf","year":"2021","journal-title":"Vascular and endovascular surgery"},{"issue":"8","key":"6","first-page":"176","article-title":"Differences in clinical and echocardiographic variables and mortality predictors among older patients with pulmonary embolism","volume":"33","author":"\u00d6. Altu\u011f","year":"2021","journal-title":"Aging clinical and experimental research"},{"issue":"42","key":"7","first-page":"10","article-title":"Progrostic impact of a pre-existing heart failure with preserved ejection fraction in patients with APE or paroxysmal atrial fibrillation","volume":"28","author":"N. Tufano","year":"2021","journal-title":"European Journal of Preventive Cardiology"},{"issue":"55","key":"8","first-page":"120","article-title":"Use and clinical outcome of veno-arterial extracorporeal membrane oxygenation in patients with APE and cardiopulmonary resuscitation","volume":"10","author":"L. Hobohm","year":"2021","journal-title":"European Heart Journal Acute Cardiovascular Care"},{"issue":"55","key":"9","first-page":"120","article-title":"Percutaneous catheter-directed treatment in intermediate-high risk APE. Hemodynanical and right heart function-related parameters changes and short-term outcomes","volume":"10","author":"J. Gradoli Palmero","year":"2021","journal-title":"European Heart Journal. Acute Cardiovascular Care"},{"issue":"52","key":"10","first-page":"183","article-title":"Pulmonary artery obstruction index, pulmonary artery diameter and right ventricle strain as prognostic CT findings in patient with APE","volume":"22","author":"S. Hajiahmadi","year":"2021","journal-title":"Radiolog\u00eda"},{"issue":"4","key":"11","first-page":"1920","article-title":"Massive pulmonary embolism and thrombus-in-transit via a patent foramen ovale: a case report of successful use of extracorporeal membrane oxygenation to manage post-embolectomy severe right ventricular dysfunction","volume":"5","author":"S. Helen","year":"2021","journal-title":"European heart journal Case reports"},{"issue":"3","key":"12","first-page":"192","article-title":"APE severity assessment evaluated with dual energy CT perfusion compared to conventional CT angiographic measurements","volume":"11","author":"J. Samir","year":"2021","journal-title":"Diagnostics"},{"issue":"3","key":"13","first-page":"1290","article-title":"Analysis of the 60\/60 sign and other right ventricular parameters by 2D transthoracic echocardiography as adjuncts to diagnosis of APE","volume":"13","author":"R. Shah Bhupesh","year":"2021","journal-title":"Cureus"},{"issue":"31","key":"14","first-page":"491","article-title":"Right ventricular echocardiographic parameters associated with prothrombotic abnormalities in normotensive patients with APE","volume":"333","author":"J. S. Agnieszka","year":"2021","journal-title":"International Journal of Cardiology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.22995"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-021-01917-2"},{"issue":"1","key":"17","first-page":"483","article-title":"A predictive tool for the assessment of right ventricular dysfunction in non-high-risk patients with APE","volume":"21","author":"G. Yizhuo","year":"2021","journal-title":"BMC Pulmonary Medicine"},{"issue":"42","key":"18","first-page":"1905","article-title":"Importance of computed tomography pulmonary angiography for predict 30-day mortality in APE patients","volume":"8","author":"C. Narumol","year":"2021","journal-title":"European Journal of Radiology Open"},{"issue":"1","key":"19","first-page":"129","article-title":"Rapid dynamic bedside assessment of pulmonary perfusion defect by electrical impedance tomography in a patient with acute massive pulmonary embolism","volume":"11","author":"Y. Siyi","year":"2021","journal-title":"Pulmonary Circulation"},{"issue":"6","key":"20","first-page":"668","article-title":"Clinical significance of echocardiographic evaluation of right ventricular function and curative effect in patients with APE","volume":"29","author":"S. Binhao","year":"2020","journal-title":"Journal of Cardiovascular Rehabilitation Medicine"},{"issue":"12","key":"21","first-page":"192","article-title":"Index of cardiac-electrophysiological balance and the effects of thrombolytic therapy on the electrocardiogram of patients with pulmonary embolism","volume":"66","author":"A. Yakup","year":"2020","journal-title":"Revista Da Associacao Medica Brasileira"},{"issue":"11","key":"22","first-page":"829","article-title":"Echocardiographic evaluation of left ventricular diastolic function before and after thrombolysis in patients with APE","volume":"22","author":"Q. Shiyang","year":"2020","journal-title":"Journal of Clinical Ultrasonic Medicine"},{"issue":"21","key":"23","first-page":"21","article-title":"The value of echocardiography and lower extremity deep vein echocardiography in the diagnosis of APE","volume":"14","author":"X. Mei","year":"2020","journal-title":"Modern drug application in China"},{"issue":"19","key":"24","first-page":"5","article-title":"Evaluation of right ventricular function in patients with APE by multi-slice spiral CT and echocardiography","volume":"24","author":"W. Huadong","year":"2020","journal-title":"Journal of practical Clinical Medicine"},{"issue":"16","key":"25","article-title":"Study on the correlation between echocardiography and CT pulmonary embolism index in patients with APE","volume":"42","author":"C. Feifei","year":"2020","journal-title":"Zhejiang medicine"},{"issue":"4","key":"26","first-page":"580","article-title":"Echocardiographic evaluation of left ventricular function in patients with different risk of APE","volume":"32","author":"Q. Shiyang","year":"2020","journal-title":"Western medicine"},{"issue":"2","key":"27","first-page":"285","article-title":"Application value of echocardiography combined with CK, CK-MB, LDH and AST in APE","volume":"33","author":"M. Xiangqian","year":"2020","journal-title":"Medical theory and practice"},{"issue":"412","key":"28","first-page":"129","article-title":"The accuracy of non-radiologists at identifying signs of right heart strain on computer tomography angiography (CTA) of patients with APE (PE)","volume":"201","author":"S. Pettigrew","year":"2020","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"6","key":"29","first-page":"149","article-title":"Correction to: Septal bowing and pulmonary artery diameter on computed tomography pulmonary angiography are associated with short-term outcomes in patients with APE","volume":"26","author":"L. M. Dam","year":"2019","journal-title":"Emergency Radiology"},{"issue":"3","key":"30","first-page":"1300","article-title":"Relationship of lower-extremity DVT density at CT venography to APE and the risk of postthrombotic syndrome","volume":"293","author":"J. Min-Jae","year":"2019","journal-title":"Radiology"},{"issue":"6","key":"31","first-page":"165","article-title":"Septal bowing and pulmonary artery diameter on computed tomography pulmonary angiography are associated with short-term outcomes in patients with APE","volume":"26","author":"L. M. Dam","year":"2019","journal-title":"Emergency Radiology"},{"issue":"52","key":"32","first-page":"1993","article-title":"New findings on pulmonary embolism from University Medical Center Mainz summarized (immediate and late impact of reperfusion therapies in APE)","volume":"21","author":"Lung Diseases and Conditions - Pulmonary Embolism","year":"2019","journal-title":"Medical Letter on the CDC & FDA"},{"issue":"34","key":"33","first-page":"119","article-title":"Diagnostic value and safety evaluation of electrocardiogram combined with echocardiography in patients with APE","volume":"35","author":"T. Li","year":"2019","journal-title":"Chinese community physician"},{"issue":"27","key":"34","first-page":"25","article-title":"Clinical study on evaluation of right ventricular systolic function in patients with APE by real-time three-dimensional echocardiography","volume":"14","author":"X. Wang Wei","year":"2019","journal-title":"Chinese practical medicine"},{"issue":"17","key":"35","first-page":"1070","article-title":"Analysis of echocardiography and myocardial zymogram in patients with APE","volume":"17","author":"M. X. Qian","year":"2019","journal-title":"Journal of community medicine"},{"issue":"26","key":"36","article-title":"Predictive value of brain natriuretic peptide on right ventricular insufficiency in patients with APE","volume":"28","author":"L. Dongmei","year":"2019","journal-title":"Journal of Modern Integrated traditional Chinese and Western Medicine"}],"updated-by":[{"DOI":"10.1155\/2023\/9791415","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:00:00Z","timestamp":1695772800000},"record-id":"55507"},{"DOI":"10.1155\/2023\/9791415","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:00:00Z","timestamp":1695772800000}}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/3483390.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/3483390.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2022\/3483390.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T19:07:28Z","timestamp":1652296048000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmm\/2022\/3483390\/"}},"subtitle":[],"editor":[{"given":"Min","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,5,11]]},"references-count":36,"alternative-id":["3483390","3483390"],"URL":"https:\/\/doi.org\/10.1155\/2022\/3483390","relation":{},"ISSN":["1748-6718","1748-670X"],"issn-type":[{"value":"1748-6718","type":"electronic"},{"value":"1748-670X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5,11]]}}}