{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:29:18Z","timestamp":1789180158558,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T00:00:00Z","timestamp":1645747200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,2,25]]},"abstract":"<jats:p>Hydrophobic acrylic intraocular lens (IOL) is the most popular material in cataract surgery. Posterior capsule opacification (PCO) is a long-term complication of cataract surgery. It can impair vision and adversely affect the prognosis of IOL delamination. The objective of this study was to perform a systematic review and meta-analysis to provide an updated evaluation of long-term complications and visual function after implantation with hydrophobic acrylic and silicone intraocular lenses. PubMed, Embase, and Cochrane Library were searched from January 2000 until March 2021. Randomized controlled trials (RCTs) and retrospective studies were finally included. The main outcomes were PCO value and neodymium-doped yttrium aluminum garnet (Nd\u2009:\u2009YAG) capsulotomy rate. Subgroup analysis was performed to compare hydrophobic acrylic and silicone IOLs during the follow-up period. Sensitivity analysis was also performed. The meta-analysis included a total of 17 studies. When the follow-up period was considered, the results of the analysis revealed higher PCO value (Group 3: standardized mean difference (SMD), \u22120.59; 95% confidence interval (CI), \u22120.90 to \u22120.28) and Nd\u2009:\u2009YAG capsulotomy rate (Group 3: risk ratio (RR), 0.60; 95% CI, 0.40\u20130.89) for hydrophobic acrylic IOLs than silicone IOLs during a long-term (\u22656 years) follow-up. In conclusion, both the PCO value and the Nd\u2009:\u2009YAG capsulotomy rates were higher in hydrophobic acrylic IOLs group than the silicone IOLs group at long-term use (more than 6 years) after implantation.<\/jats:p>","DOI":"10.1155\/2022\/3570399","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T00:20:07Z","timestamp":1645834807000},"page":"1-10","source":"Crossref","is-referenced-by-count":17,"title":["Posterior Capsule Opacification after Cataract Surgery via Implantation with Hydrophobic Acrylic Lens Compared with Silicone Intraocular Lens: A Systematic Review and Meta-Analysis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7262-921X","authenticated-orcid":true,"given":"Ye Rin","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Medical Devices Industry, Dongguk University-Seoul (04620), 26 Pil-dong 3-ga Jung-gu, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4898-470X","authenticated-orcid":true,"given":"Yoo Na","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology, Dongguk University-Biomedical Campus (10326), 32 Dongguk-ro Ilsandong-gu, Goyang-si, Gyeonggi-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6457-989X","authenticated-orcid":true,"given":"Sung Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medical Devices Industry, Dongguk University-Seoul (04620), 26 Pil-dong 3-ga Jung-gu, Seoul, Republic of Korea"},{"name":"Department of Medical Biotechnology, Dongguk University-Biomedical Campus (10326), 32 Dongguk-ro Ilsandong-gu, Goyang-si, Gyeonggi-do, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(05)70803-5"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.03.032"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(17)30544-5"},{"key":"4","article-title":"Cataract data and statistics","author":"National Eye Institute","year":"2021"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/icu.0000000000000719"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.11.044"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2013.07.039"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.11.006"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.22336\/rjo.2018.29"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0220498"},{"key":"11","article-title":"Interventions for preventing posterior capsule opacification","volume":"17","author":"O. 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