{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:03:44Z","timestamp":1767168224831,"version":"build-2238731810"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Key Research Projects of Medical Science in Hebei Province","award":["20221223"],"award-info":[{"award-number":["20221223"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2022,7,25]]},"abstract":"<jats:p>\n                    This study was aimed at exploring the risk factors for thoracotomy in patients undergoing thoracoscopic resection of lung cancer and further analyzing the factors affecting the prognosis of patients. Ninety-six patients with non-small-cell lung cancer who underwent thoracoscopic pulmonary resection were recruited as the subjects, and they were enrolled into the thoracoscopic group (\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>n<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>88<\/a:mn>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    ) and the thoracotomy group (\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>n<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>8<\/c:mn>\n                      <\/c:math>\n                    <\/jats:inline-formula>\n                    ) according to whether thoracotomy was performed. Univariate analysis and logistic multivariate regression were performed to analyze the risk factors for conversion to thoracotomy, and nomogram prediction model was employed to analyze the prognostic factors. The results revealed that the proportion of patients over 65 years old, with history of coronary heart disease, diabetes, and pulmonary tuberculosis, etc., in the thoracotomy group and the thoracoscopic group was significantly different (\n                    <jats:inline-formula>\n                      <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                      <\/e:math>\n                    <\/jats:inline-formula>\n                    ). There were statistically significant differences in the development of interlobular cleft, pleural adhesion, tumor\n                    <jats:inline-formula>\n                      <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mtext>diameter<\/g:mtext>\n                        <g:mo>&gt;<\/g:mo>\n                        <g:mn>3.5<\/g:mn>\n                      <\/g:math>\n                    <\/jats:inline-formula>\n                    \u2009cm, vascular and lymph node invasion, and tumor TNM stage between the thoracotomy group and the thoracoscopic group (\n                    <jats:inline-formula>\n                      <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                      <\/i:math>\n                    <\/jats:inline-formula>\n                    ). Overall, the age of\n                    <jats:inline-formula>\n                      <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mtext>patients<\/k:mtext>\n                        <k:mo>\u2265<\/k:mo>\n                        <k:mn>65<\/k:mn>\n                      <\/k:math>\n                    <\/jats:inline-formula>\n                    years old, tumor\n                    <jats:inline-formula>\n                      <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mtext>diameter<\/m:mtext>\n                        <m:mo>&gt;<\/m:mo>\n                        <m:mn>3.5<\/m:mn>\n                      <\/m:math>\n                    <\/jats:inline-formula>\n                    \u2009cm, hypoplasia of interlobular fissure, history of pulmonary tuberculosis, pleural adhesion, and TNM stage IIIa were all independent risk factors for thoracoscopic resection of lung cancer to thoracotomy. Cox model and nomogram prediction model analysis showed that surgery methods, tumor\n                    <jats:inline-formula>\n                      <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mtext>diameter<\/o:mtext>\n                        <o:mo>&gt;<\/o:mo>\n                        <o:mn>3.5<\/o:mn>\n                      <\/o:math>\n                    <\/jats:inline-formula>\n                    \u2009cm, chemotherapy\n                    <jats:inline-formula>\n                      <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mtext>cycle<\/q:mtext>\n                        <q:mo>&lt;<\/q:mo>\n                        <q:mn>4<\/q:mn>\n                      <\/q:math>\n                    <\/jats:inline-formula>\n                    , chemotherapy, and TNM stage IIIa were all independent factors influencing the prognosis of patients undergoing thoracoscopic lung cancer resection. This nomogram prediction model had high application value in patient prognosis prediction.\n                  <\/jats:p>","DOI":"10.1155\/2022\/3628335","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T14:50:06Z","timestamp":1658760606000},"page":"1-10","source":"Crossref","is-referenced-by-count":2,"title":["Nomogram Prediction Model Analysis of Risk Factors for Conversion to Thoracotomy after Thoracoscopic Resection of Lung Cancer and Prognostic Value of Lung Cancer"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4811-4288","authenticated-orcid":true,"given":"Peng","family":"Su","sequence":"first","affiliation":[{"name":"Department of Thoracic Fifth, Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011 Hebei, 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7150-3401","authenticated-orcid":true,"given":"Chao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Fifth, Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011 Hebei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8658-4136","authenticated-orcid":true,"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Fifth, Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011 Hebei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2955-3333","authenticated-orcid":true,"given":"Ziqiang","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Thoracic Fifth, Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011 Hebei, 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