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Vancomycin became a viable therapy option due to MRSA resistance to methicillin medicines. One of the well\u2010informed antibacterial compounds with wideband antibacterial activity is silver nanoparticles (AgNPs). AgNPs are thus suitable candidates for usage in conjunction alongside vancomycin to increase its antibacterial effect. The goal of the present research work is to boost the antibacterial potency of the glycopeptide antibiotic vancomycin towards Gram\u2010positive (Staphylococcus aureus) but also Gram\u2010negative (Escherichia coli) bacteria. The chemical reduction approach is used to create a colloidal solution of silver nanoparticles utilizing silver nitrate as a precursor in the environment of the ionic surfactant trisodium citrate that serves as covering including reducing reagent. Vancomycin was used to functionalize the synthesized nanoparticles and create the nanodrug complex (Van@AgNPs). The synergistic antibacterial potential of silver nanoparticles coated with vancomycin on both test pathogens was investigated using the agar well diffusion technique. The antibacterial potency for both classes of bacteria has significantly increased, according to the well diffusion test. It has been noted that this improvement is synergistic instead of additive.<\/jats:p>","DOI":"10.1155\/2022\/3682757","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T05:10:27Z","timestamp":1661145027000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["[Retracted] Vancomycin as an Antibacterial Agent Capped with Silver Nanoparticles: An Experimental Potential Analysis"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5043-366X","authenticated-orcid":false,"given":"Mohsina","family":"Patwekar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faheem","family":"Patwekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4532-9128","authenticated-orcid":false,"given":"Saad","family":"Alghamdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3585-0828","authenticated-orcid":false,"given":"Mehnaz","family":"Kamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7929-7748","authenticated-orcid":false,"given":"Mamdouh","family":"Allahyani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7580-8667","authenticated-orcid":false,"given":"Mazen","family":"Almehmadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3573-0364","authenticated-orcid":false,"given":"Ahmed","family":"Kabrah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6744-6259","authenticated-orcid":false,"given":"Anas S.","family":"Dablool","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahad Amer","family":"Alsaiari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talha","family":"Jawaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0015-7414","authenticated-orcid":false,"given":"Anuradha","family":"Medikeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krupa","family":"Samuel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8514-2064","authenticated-orcid":false,"given":"Fahadul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,21]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114204"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-823876-9.00009-3"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1764647"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3636481"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/5968131"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0142-9612(94)90028-0"},{"key":"e_1_2_6_7_2","first-page":"318","article-title":"Activity guided separation of phytoconstituents from the flowers of Ichnocarpus frutescens L. and evaluation for antioxidant property","volume":"1","author":"Patwekar F. 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