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Therefore, strategies to modulate intestinal hemostasis had inspired an important research trend in the process of preventing and treating radiation enteritis. Based on the structural characteristics of montmorillonite (MMT) and the hemostatic drug tranexamic acid (TXA) which was used clinically to treat enteritis, the tranexamic acid\u2010montmorillonite composite material (TXA\u2010MMT) was prepared through intercalation composite technology. According to the analysis of FTIR, XRD, TG\u2010DTG, SEM, and XRF, the prepared TXA\u2010MMT was verified that tranexamic acid could intercalate into layers of montmorillonite. To evaluate the biocompatibility, two experiments were conducted by in vitro hemolysis and in vitro cytotoxicity experiments and results showed that TXA\u2010MMT exhibited good visible biocompatibility. Activated partial thromboplastin time, prothrombin time, and in vitro clotting time were adopted to determine the hemostatic effect of TXA\u2010MMT. Compared with other groups, TXA\u2010MMT revealed a significant decrease in clotting time variations, APTT, and PT. In addition, to investigate the preventive effect of TXA\u2010MMT by the intervention of radiation enteritis mice, inflammatory factors IL\u20101<jats:italic>\u03b2<\/jats:italic>, IL\u20106, and TNF\u2010<jats:italic>\u03b1<\/jats:italic> and the content of endotoxin in the serum of mice were detected. It demonstrated that TXA\u2010MMT reduced the levels of these factors. Besides, the expression and the pathological changes of the small intestine tissue of mice were relieved. Our findings suggests that TXA\u2010MMT as a promising intercalation composite has a great potential for application in the field of intestinal hemostasis.<\/jats:p>","DOI":"10.1155\/2022\/3963681","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T19:51:35Z","timestamp":1646077895000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["[Retracted] Evaluation of Novel Tranexamic Acid\/Montmorillonite Intercalation Composite, as a New Type of Hemostatic 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